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| Title / Description | Anastrozole/Fulvestrant/Gefitinib neoadjuvant therapy of estrogen receptor positive breast cancer patients: tumor core biopsies |
| Accession | GDS4093 |
| Summary | Analysis of pre and post (3 wk) tumor core biopsies of postmenopausal women with ER+, HER2- breast cancer (BC) in neoadjuvant trial of anastrozole and fulvestrant with/without gefitinib. Results provide insight into mechanisms of resistance and inhibition of hormone receptors targeted in BC therapy. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | pre and post (3 wk) tumor core biopsies of postmenopausal women with ER+, HER2 breast cancer (BC) |
| Perturbation | Gefitinib |
| Disease | Breast Cancer |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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