TKI gene signatures (150)

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Title Organism Platform Optional Metadata
1 Cirrhotic liver response to the ... Rattus norvegicus Rattus norvegicus
Cell Liver
Perturbation Sunitinib
Disease Cirrhosis
2 Expression data from breast cancer tumors ... Homo sapiens Homo sapiens
Cell Tumor
Perturbation Sunitinib
Disease Breast cancer
3 Sunitinib treatment exacerbates intratumoral ... Homo sapiens Homo sapiens
Cell Kidney
Perturbation Sunitinib
Disease Renal cancer
4 Gene expression profiles of Sunitinib-treated ... Homo sapiens Homo sapiens
Cell BTIC (brain tumor ...
Perturbation Sunitinib
Concentration 1uM
5 Effect of Sunitinib treatment withdrawal on ... Mus musculus Mus musculus
Cell MDAMB231 tumors
Perturbation Sunitinib
Concentration 40mg/kg/day
6 Analysis of Gene Expression of Human Renal ... Homo sapiens Homo sapiens
Cell Renal cell tumor
Perturbation Sunitinib
Relevant information Surgery Vs. ...
7 Differentiation of Mammary Tumors by SKI-606 ... Mus musculus Mus musculus
Cell Mammary ...
Perturbation Bostutinib
Concentration 100 mg/kg
8 Global gene expression changes in ... Homo sapiens Homo sapiens
Cell K562
Perturbation Dasatinib
Time 4hrs
Concentration 100nM
9 Global gene expression changes in ... Homo sapiens Homo sapiens
Cell K562
Perturbation Dasatinib
Time 8hrs
Concentration 100nM
10 Global gene expression changes in ... Homo sapiens Homo sapiens
Cell K562
Perturbation Dasatinib
Time 24hrs
Concentration 100nM
11 Fasting potentiates the anticancer activity of ... Homo sapiens Homo sapiens
Cell Lung (H3122 non small ...
Perturbation Crizotinib
Time 72hrs
Concentration 400nM
12 Improved antitumor activity of immunotherapy ... Mus musculus Mus musculus
Cell SM1 tumor
Perturbation Dabratinib
13 Spectrum, clinical correlates and clinical ... Homo sapiens Homo sapiens
Cell Melanoma tumor
Perturbation Dabrafenib
Disease Melanoma
14 Anti-proliferative effects of continued ... Homo sapiens Homo sapiens
Cell SKMel28
Perturbation Dabrafenib
Time 24hrs
Concentration 100nM
15 Anti-proliferative effects of continued ... Homo sapiens Homo sapiens
Cell SKMel28
Perturbation Trametinib
Time 24hrs
Concentration 10nM
16 Spectrum, clinical correlates and clinical ... Homo sapiens Homo sapiens
Cell BRAF V600E
Perturbation Vemurafenib
Disease Melanoma
17 Braf inhibitors reverse the unique molecular ... Homo sapiens Homo sapiens
Cell BRAF-V600E
Perturbation Vemurafenib
Time 48hrs
Concentration 1000nM
18 Gene expression profiling of HDLM-2 Hodgkin ... Homo sapiens Homo sapiens
Cell HDLM2
Perturbation Sorafenib
Time 24hrs
Concentration 5uM
Disease Hodgkin lymphoma
19 Gene expression profiling of L-540 Hodgkin ... Homo sapiens Homo sapiens
Cell L540
Perturbation Sorafenib
Time 24hrs
Concentration 5uM
Disease Hodgkin lymphoma
20 Gene expression profiling of HD-MyZ Hodgkin ... Homo sapiens Homo sapiens
Cell HDMyZ
Perturbation Sorafenib
Time 24hrs
Concentration 5uM
Disease Hodgkin lymphoma
21 Gene expression analysis of Hodgkin lymphoma ... Homo sapiens Homo sapiens
Cell HDLM2
Perturbation Sorafenib
Time 5uM
Concentration 24hrs
Disease Hodgkin lymphoma
22 Sorafenib treatment of FLT3-ITD+ acute myeloid ... Homo sapiens Homo sapiens
Cell CD33+CD34+ myeloblast
Perturbation Sorafenib
Time Twice daily
Concentration 200-400mg
Disease AML
23 Expression in irradiated MEFs exposed to ... Mus musculus Mus musculus
Cell MEFs (irradiated)
Perturbation Nilotinib
Concentration 16nM
24 Imatinib and Nilotinib induced molecular ... Homo sapiens Homo sapiens
Cell K562
Perturbation Nilotinib
Concentration 0.05uM
Disease CML
25 Gene expression analysis in EGFR-mutant NSCLC ... Homo sapiens Homo sapiens
Cell PC9
Perturbation Erlotinib
Concentration 2uM
26 Gene expression analysis in EGFR-mutant NSCLC ... Homo sapiens Homo sapiens
Cell HCC827
Perturbation Erlotinib
Concentration 2uM
27 Whole transcriptome analysis of erlotinib ... Homo sapiens Homo sapiens
Cell HCC827
Perturbation Erlotini
Time 6hrs
28 Genome-wide analysis of EGFR inhibitor ... Homo sapiens Homo sapiens
Cell SQ20B
Perturbation Erlotinib
Time 48hrs
Concentration 5uM
29 Genome-wide analysis of EGFR inhibitor ... Homo sapiens Homo sapiens
Cell FADU
Perturbation Erlotinib
Time 48hrs
Concentration 5uM
30 Expression data from EGFR WT or EGFR mutant ... Homo sapiens Homo sapiens
Cell HCC78
Perturbation Erlotinib
Time 24hrs
Concentration 1mM
31 Genome-wide analysis of EGFR inhibitor ... Homo sapiens Homo sapiens
Cell Cal 27
Perturbation Erlotinib
Time 48hrs
Concentration 5uM
32 Microarray study to understand acquired ... Homo sapiens Homo sapiens
Cell HCC827
Perturbation Erlotinib
Time 12hrs
33 Dynamic re-wiring of apoptotic signaling ... Homo sapiens Homo sapiens
Cell BT20
Perturbation Erlotinib
Time 0.5hrs
Concentration 10uM
34 Dynamic re-wiring of apoptotic signaling ... Homo sapiens Homo sapiens
Cell BT20
Perturbation Erlotinib
Time 1 day
Concentration 10uM
35 Targeting FAK and EGFR/HER-2 with small ... Homo sapiens Homo sapiens
Cell SKBR3
Perturbation Lapatinib
Concentration 5uM
36 Systems analysis of adaptive responses to MAP ... Homo sapiens Homo sapiens
Cell DM331
Perturbation Lapatinib
Time 8hrs
Disease Melanoma
37 Lapatinib effect on lapatinib-resistant ... Homo sapiens Homo sapiens
Cell SKBR3
Perturbation Lapatinib
Concentration 0.1uM
Relevant information Lapatinib sensitive
38 Lapatinib effect on lapatinib-resistant ... Homo sapiens Homo sapiens
Cell SKBR3
Perturbation Lapatinib
Concentration 1uM
Relevant information Lapatinib sensitive
39 Lapatinib-resistant HER2-positive breast tumor ... Homo sapiens Homo sapiens
Cell BT474
Perturbation Lapatinib
Concentration 1uM
40 Lapatinib-resistant HER2-positive breast tumor ... Homo sapiens Homo sapiens
Cell BT474J4
Perturbation Lapatinib
Concentration 1uM
41 Bone marrow microenvironment effect on ... Homo sapiens Homo sapiens
Cell Blood
Perturbation Imatinib
Concentration 5uM
42 Chronic myelogenous leukemia response to ... Homo sapiens Homo sapiens
Cell CD34+ cells ...
Perturbation Imatinib
Disease CML
43 Chronic myelogenous leukemia CD34+CD38- cells ... Homo sapiens Homo sapiens
Cell CD34+CD38 cells
Perturbation Imatinib
Disease Chronic myelogenous ...
44 Imatinib effects on chronic myelogenous ... Homo sapiens Homo sapiens
Cell CD34+ cells
Perturbation Imatinib
45 Imatinib induces mesenchymal stem ... Mus musculus Mus musculus
Cell MSCs
Perturbation Imatinib
Time 96hrs
46 Imatinib induces mesenchymal stem ... Mus musculus Mus musculus
Cell MSCs
Perturbation Imatinib
Time 32hrs
47 Imatinib induces mesenchymal stem ... Mus musculus Mus musculus
Cell MSCs
Perturbation Imatinib
Time 64hrs
48 An EphB-Abl signaling pathway important for ... Mus musculus Mus musculus
Cell Colon
Perturbation Imatinib
Time 3hrs
49 Combined inhibition of TGFβ and PDGF signaling ... Mus musculus Mus musculus
Cell Lung
Perturbation Imatinib
50 An EphB-Abl signaling pathway important for ... Mus musculus Mus musculus
Cell Colon
Perturbation Imatinib
Time 12hrs
51 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC1143
Perturbation Ruxolitinib
Time 4hrs
Concentration 1uM
52 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC1143
Perturbation Ruxolitinib
Time 24hrs
Concentration 1uM
53 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell SUM159PT
Perturbation Ruxolitinib
Time 4hrs
Concentration 1uM
54 First ruxolitinib treatment of human alopecia ... Homo sapiens Homo sapiens
Cell Skin
Perturbation Ruxolitinib
Disease Alopecia
55 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell SUM159PT
Perturbation Ruxolitinib
Time 24hrs
Concentration 1uM
56 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC38
Perturbation Ruxolitinib
Time 4hrs
Concentration 1uM
57 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC38
Perturbation Ruxolitinib
Time 24hrs
Concentration 1uM
58 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC70
Perturbation Ruxolitinib
Time 4hrs
Concentration 1uM
59 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC70
Perturbation Ruxolitinib
Time 24hrs
Concentration 1uM
60 Effect of ruxolitinib treatment on gene ... Homo sapiens Homo sapiens
Cell HCC70
Perturbation Ruxolitinib
Time 24hrs
Concentration 1uM
61 Capturing drug responses by quantitative ... Homo sapiens Homo sapiens
Cell MCF7
Perturbation Gefitinib
Time 6hrs
Concentration 1uM
Disease Breast cancer
62 EGFR Isoforms and Gene Regulation in Human ... Homo sapiens Homo sapiens
Cell Hec50co
Perturbation Gefitinib
Time 12hrs
Concentration 1uM
Disease Endometrial ...
63 EGFR Isoforms and Gene Regulation in Human ... Homo sapiens Homo sapiens
Cell Hec50co
Perturbation Gefitinib
Time 24hrs
Concentration 1uM
Disease Endometrial ...
64 EGFR Isoforms and Gene Regulation in Human ... Homo sapiens Homo sapiens
Cell Ishikawa H
Perturbation Gefitinib
Time 12hrs
Concentration 1uM
Disease Endometrial ...
65 EGFR Isoforms and Gene Regulation in Human ... Homo sapiens Homo sapiens
Cell Ishikawa H
Perturbation Gefitinib
Time 24hrs
Concentration 1uM
Disease Endometrial ...
66 Establishment of Afatinib-Resistant Non-Small ... Homo sapiens Homo sapiens
Cell BR161
Perturbation Afatinib
Time 48hrs
Concentration 10nM
Relevant information Resistant cell line
67 Establishment of Afatinib-Resistant Non-Small ... Homo sapiens Homo sapiens
Cell BR161
Perturbation Afatinib
Time 48hrs
Concentration 100nM
Relevant information Resistant cell line
68 Establishment of Afatinib-Resistant Non-Small ... Homo sapiens Homo sapiens
Cell BR161
Perturbation Afatinib
Time 48hrs
Concentration 1000nM
Relevant information Resistant cell line
69 Prevention of Mouse AA with IL-15 pathway ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib
Disease 13 weeks
70 Prevention of Mouse AA with IL-15 pathway ... Mus musculus Mus musculus
Cell Skin
Perturbation Ruxolitinib
Disease 6 weeks
71 Treatment of established mouse AA with topical ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib
Time 6 weeks
72 Treatment of established mouse AA with topical ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib
Time 12 weeks
73 Treatment of established mouse AA with topical ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib
Time 24 weeks
74 Gene expression in Vemurafenib-treated A375 ... Homo sapiens Homo sapiens
Cell A375
Perturbation Vemurafenib
Concentration 1uM
Disease Melanoma
75 Gene expression in Vemurafenib-treated A375 ... Homo sapiens Homo sapiens
Cell A2058
Perturbation Vemurafenib
Concentration 1uM
Disease Melanoma
76 Oncogenic BRAF harboring melanoma cell line ... Homo sapiens Homo sapiens
Cell A375
Perturbation Vemurafenib
Concentration 10uM
Disease Melanoma
77 Braf inhibitors reverse the unique molecular ... Homo sapiens Homo sapiens
Cell Peripheral blood
Perturbation Vemurafenib
Time 48hrs
Concentration 1000nM
Disease Hairy cell leukemia
78 Braf inhibitors reverse the unique molecular ... Homo sapiens Homo sapiens
Cell Peripheral blood
Perturbation Vemurafenib
Time 72hrs
Concentration 1000nM
Disease Hairy cell leukemia
79 Parent vs. Induced drug tolerant cells ... Homo sapiens Homo sapiens
Cell WM164
Perturbation Vemurafenib
Time 16 days
Concentration 500nM
Disease Melanoma
80 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SKMEL28
Perturbation Vemurafenib
Time 1hr
Concentration 2uM
81 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SKMEL28
Perturbation Vemurafenib
Time 6hrs
Concentration 2uM
82 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SKMEL28
Perturbation Vemurafenib
Time 48hrs
Concentration 2uM
83 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SW1736
Perturbation Vemurafenib
Time 1hr
Concentration 2uM
84 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SW1736
Perturbation Vemurafenib
Time 6hrs
Concentration 2uM
85 Relief of feedback inhibition of HER3 ... Homo sapiens Homo sapiens
Cell SW1736
Perturbation Vemurafenib
Concentration 2uM
Time 48hrs
86 Cirrhotic liver response to the ... Rattus norvegicus Rattus norvegicus
Cell Liver
Perturbation Sunitinib
Disease Cirrhosis
87 Expression data from renal cancer xenograft ... Homo sapiens Homo sapiens
Cell KURC1
Perturbation Sunitinib
Concentration 40mg/day
Relevant information Sunitinib resistant ...
88 Gene expression changes during resistance ... Homo sapiens Homo sapiens
Cell 786O
Perturbation Sunitinib
Disease Renal cell carcinoma
Relevant information Sunitinib resistant ...
89 Gene expression changes during resistance ... Homo sapiens Homo sapiens
Cell A498
Perturbation Sunitinib
Disease Renal cell carcinoma
Relevant information Sunitinib resistant ...
90 GSE20921 Differentiation of Mammary Tumors by ... Mus musculus Mus musculus
Cell Mammary
Perturbation Bosutinib
Concentration 100mg/kg
91 Predominance of MAPK reactivation in early ... Homo sapiens Homo sapiens
Cell Skin (BRAF V600K)
Perturbation Dabrafenib
Disease Melanoma
92 Gene expression profiling of HDLM-2 Hodgkin ... Homo sapiens Homo sapiens
Cell HDLM2
Perturbation Sorafenib
Time 24hrs
Concentration 5uM
93 Gene expression profiling of L-540 Hodgkin ... Homo sapiens Homo sapiens
Cell L540
Perturbation Sorafenib
Time 24hrs
Concentration 5uM
94 GSE43053 - The multikinase inhibitor Sorafenib ... Rattus norvergicus Rattus norvergicus
Cell LCSC-2
Perturbation Sorafenib
Disease Hepatocholangiocarcinoma
95 Synthetic lethal screening with small molecule ... Homo sapiens Homo sapiens
Cell VMM39 (mutant Ras)
Perturbation Sorafenib
96 Lapatinib effect on lapatinib-resistant ... Homo sapiens Homo sapiens
Cell SKBR3R
Perturbation Lapatinib
Concentration 0.1uM
Relevant information Lapatinib resistant
97 Lapatinib effect on lapatinib-resistant ... Homo sapiens Homo sapiens
Cell SKBR3R
Perturbation Lapatinib
Concentration 1uM
Relevant information Lapatinib resistant
98 Lapatinib-resistant HER2-positive breast tumor ... Homo sapiens Homo sapiens
Cell BT474J4
Perturbation Lapatinib
Concentration 1uM
Relevant information Acquired ...
99 Systems analysis of adaptive responses to MAP ... Homo sapiens Homo sapiens
Cell A375
Perturbation Lapatinib
Concentration 2uM
100 Systems analysis of adaptive responses to MAP ... Homo sapiens Homo sapiens
Cell HT144
Perturbation Lapatinib
Concentration 2uM
101 Systems analysis of adaptive responses to MAP ... Homo sapiens Homo sapiens
Cell SKMEL28
Perturbation Lapatinib
Concentration 2uM
102 Systems analysis of adaptive responses to MAP ... Homo sapiens Homo sapiens
Cell SKMEL24
Perturbation Lapatinib
Concentration 2uM
103 Anastrozole/Fulvestrant/Gefitinib neoadjuvant ... Homo sapiens Homo sapiens
Cell pre and post (3 wk) ...
Perturbation Gefitinib
Disease Breast Cancer
104 Imatinib treatment of chronic myeloid leukemia ... Homo sapiens Homo sapiens
Cell KU812, KCL-22, JURL-MK1
Perturbation Imatinib
Disease Chronic myeloid leukemia
105 Spectrum, clinical correlates and clinical ... Homo sapiens Homo sapiens
Cell Melanoma BRAF V600E
Perturbation Dabrafenib
Disease Melanoma
106 Anti-proliferative effects of continued ... Homo sapiens Homo sapiens
Cell SKMel28
Perturbation Dabrafenib 100nM
107 Acute myeloid leukemia cell line Kasumi-1 ... Homo sapiens Homo sapiens
Cell AML cell line
Perturbation Dasatinib
Disease Leukemia
108 Imatinib mesylate effect on EOL-1 eosinophilic ... Homo sapiens Homo sapiens
Cell EOL1 eosinophilic ...
Perturbation Imatinib 1 uM - 6 hrs
Disease Leukemia
109 Imatinib mesylate effect on patient peripheral ... Homo sapiens Homo sapiens
Cell PTCL/NOS cells
Perturbation Imatinib 1 uM - 6 hrs
Disease Peripheral T-cell ...
110 Imatinib mesylate effect on bone marrow ... Homo sapiens Homo sapiens
Cell Bone marrow
Perturbation Imatinib
Disease Chronic myeloid leukemia
111 Physiologic Hypoxia Promotes Maintenance of ... Homo sapiens Homo sapiens
Cell CD34+ CML cells
Perturbation Imatinib 96 hrs - ...
112 Physiologic Hypoxia Promotes Maintenance of ... Homo sapiens Homo sapiens
Cell CD34+ CML cells
Perturbation Imatinib 24 hrs - ...
113 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 2 hrs
114 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 4 hrs
115 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 6hrs
116 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 9 hrs
117 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 12 hrs
118 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 24 hrs
119 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 18hrs
120 Detection of Treatment-Induced Changes in ... Homo sapiens Homo sapiens
Cell GISTT1 cells
Perturbation Imatinib 10 uM - 48 hrs
121 Imatinib Treatment of GIST882 Homo sapiens Homo sapiens
Cell GIST882 Cell line
Perturbation Imatinib 1 uM - 8 hrs
122 Microarray study to understand acquired ... Homo sapiens Homo sapiens
Cell ER3 nonsmall cell ...
Perturbation Erlotinib 1 uM - 12hrs
123 Microarray study to understand acquired ... Homo sapiens Homo sapiens
Cell T152 - non-small cell ...
Perturbation Erlotinib 1 uM - 12 hrs
124 Role and function of Bach2 in BCR-ABL1 driven ... Mus musculus Mus musculus
Cell preB cells (BCR-ABL1 ...
Perturbation Imatinib 2uM - 16 hrs
125 Imatinib and Nilotinib induced molecular ... Homo sapiens Homo sapiens
Cell K562 cells
Perturbation Imatinib 0.5 uM - 24 hrs
126 CD34+ Hematopoetic Stem cells (expressing ... human human
Cell CD34+ Hematopoetic ...
Perturbation Imatinib - 4 hrs
127 Imatinib mesylate effect on EOL-1 eosinophilic ... Homo sapiens Homo sapiens
Cell EOL1 - eosinophilic ...
Perturbation Imatinib 1 uM - 6 hrs
128 Macrophages (tumor associated macrophages ... mouse mouse
Cell Macrophages (tumor ...
Perturbation Imatinib 600 mg/L
129 Imatinib mesylate effect on EOL-1 eosinophilic ... Homo sapiens Homo sapiens
Cell primary PTCL/NOS cells
Perturbation Imatinib 1 uM - 6 hrs
130 Gene expression signature predictive of rapid ... Homo sapiens Homo sapiens
Cell GIST Tumor
Perturbation Imatinib 600mg daily ...
131 Bone marrow (CD34+ cells)_Imatinib human human
Cell Bone marrow (CD34+ cells)
Perturbation Imatinib
132 CD34+ cells (Philadelphia +)_Imatinib _Chronic ... human human
Cell CD34+ cells ...
Perturbation Imatinib
Disease Chronic myelogenous ...
133 Gene expression profiling in BCR/ABL ... Mus musculus Mus musculus
Cell HSCs (expressing ...
Perturbation Imatinib
134 Bone marrow microenvironment effect on ... Homo sapiens Homo sapiens
Cell Bone marrow (CD34+ cells)
Perturbation Imatinib 5 uM - 96 hrs
Disease Chronic myeloid ...
135 MET Amplified Gastric Cancer Cell Lines +/- ... Homo sapiens Homo sapiens
Cell MKN45 Gastric Cancer ...
Perturbation Crizotinib 1 uM - 24 hrs
136 MET Amplified Gastric Cancer Cell Lines +/- ... Homo sapiens Homo sapiens
Cell SNU5 Gastric Cancer ...
Perturbation Crizotinib 1 uM - 24 hrs
137 Expression data from EGFR WT or EGFR mutant ... Homo sapiens Homo sapiens
Cell NCIH23
Perturbation Erlotinib 1 mM - 24 hrs
138 Expression data from EGFR WT or EGFR mutant ... Homo sapiens Homo sapiens
Cell NCIH838
Perturbation Erlotinib 1 mM - 24 hrs
139 Expression data from EGFR WT or EGFR mutant ... Homo sapiens Homo sapiens
Cell NCIH1648
Perturbation Erlotinib 1 mM - 24 hrs
140 DNA microarray analysis following ... Homo sapiens Homo sapiens
Cell PC3 cells
Perturbation Gefitinib 60uM - 24 hrs
141 Genome-wide analysis of gefitinib short-term ... Homo sapiens Homo sapiens
Cell HCC827 NSCLC cell line
Perturbation Gefitinib 0.5 uM - ...
142 Lapatinib-resistant HER2-positive breast tumor ... Homo sapiens Homo sapiens
Cell BT474 cells
Perturbation Lapatinib
143 Oral ruxolinitib effect on alopecia areata ... Homo sapiens Homo sapiens
Cell Scalp skin
Perturbation Ruxolinitib 12 weeks
Disease Alopecia
144 Topical protein tyrosine kinase inhibitor ... Mus musculus Mus musculus
Cell Skin
Perturbation Ruxolinitib 6 weeks
145 Topical protein tyrosine kinase inhibitor ... Mus musculus Mus musculus
Cell Skin
Perturbation Ruxolinitib 12 weeks
146 Topical protein tyrosine kinase inhibitor ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib 6 weeks
147 Topical protein tyrosine kinase inhibitor ... Mus musculus Mus musculus
Cell Skin
Perturbation Tofacitinib 12 weeks
148 Genome-wide analysis of gefitinib short-term ... Homo sapiens Homo sapiens
Cell PC9 NSCLC cell line
Perturbation Gefitinib 0.5 uM - ...
149 Gene expression profiling of HDLM-2 Hodgkin ... Homo sapiens Homo sapiens
Cell HDLM2 cells
Perturbation Givinostat 100 nM - ...
150 Gene expression profiling of L-540 Hodgkin ... Homo sapiens Homo sapiens
Cell L540 cells
Perturbation Givinostat 100 nM - ...