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| Title / Description | Peroxiredoxin-like peroxidase DJ-1 knockdown effect on neuroblastoma cell line |
| Accession | GDS3750 |
| Summary | Analysis of SH-SY5Y neuroblastoma cells depleted of DJ-1, an atypical peroxiredoxin-like peroxidase. Mutations in the gene encoding DJ-1 cause autosomal recessive early-onset Parkinson disease (AREP). Results provide insight into the molecular mechanisms underlying DJ-1-mediated PD pathogenesis. |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | PARK7 |
| Cell | SHSY5Y neuroblastoma cell line |
| Perturbation | DJ1 knockdown |
| Disease | PD |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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