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| Title / Description | Breast adenocarcinoma MCF-7 cell line response to 27-Hydroxycholesterol and estradiol |
| Accession | GDS4765 |
| Summary | Analysis of MCF-7 cells treated with 27HC in the presence of E2. 27HC, a primary metabolite of cholesterol and an estrogen receptor (ER) ligand, increases ER-dependent growth in mouse models of breast cancer. Results provide insight into a relationship between hypercholesterolemia and breast cancer. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell | MCF7 |
| Perturbation | Estrogen |
| Disease | Breast cancer |
| Pert_name | Estrogen |
| Pert_type | chemical |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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