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| Title / Description | Huntington's disease Hdh knock-out and knock-in embryonic stem cells |
| Accession | GDS4533 |
| Summary | Analysis of embryonic stem cells without Hdh or with knock-in alleles with different Hdh CAG-polyglutamine repeat sizes. CAG-repeat length is inversely correlated with the age of onset of Huntington's disease (HD) symptoms in humans. Results provide insight into molecular mechanisms underlying HD. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Embryonic Stem Cells (ESCs) |
| Perturbation | Knockit (Hdh 7/111 CAG) |
| Disease | Huntington |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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