HUNTINGTON gene signatures (57)

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Title Organism Platform Optional Metadata
1 Chronic suppression of phosphodiesterase 10A ... Mus musculus Mus musculus
Gene PDE10A
Cell Hippocampus
Perturbation Knockout
Disease Huntington
2 Chronic suppression of phosphodiesterase 10A ... Mus musculus Mus musculus
Gene PDE10A
Cell Hippocampus (PDE10A KO)
Perturbation Inhibition (PDE10i)
Disease Huntington
3 Chronic suppression of phosphodiesterase 10A ... Mus musculus Mus musculus
Gene PDE10A
Cell Striatum
Perturbation Knockout
Disease Huntington
4 Chronic suppression of phosphodiesterase 10A ... Mus musculus Mus musculus
Gene PDE10A
Cell Striatum (PDE10A KO)
Perturbation Inhibition (PDE10i)
Disease Huntington
5 HdhQ111 knock-in model of Huntington's ... Mus musculus Mus musculus
Cell Cerebellum
Perturbation Knockin (HdhQ111/111)
Disease Huntington
6 HdhQ111 knock-in model of Huntington's ... Mus musculus Mus musculus
Cell Striatum
Perturbation Knockin (HdhQ111/111)
Disease Huntington
7 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Cell Embryonic Stem Cells ...
Perturbation Knockout (Hdh 7/7 CAG)
Disease Huntington
8 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Cell Embryonic Stem Cells ...
Perturbation Knockit (Hdh 7/16 CAG)
Disease Huntington
9 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Cell Embryonic Stem Cells ...
Perturbation Knockit (Hdh 7/45 CAG)
Disease Huntington
10 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Cell Embryonic Stem Cells ...
Perturbation Knockit (Hdh 7/85 CAG)
Disease Huntington
11 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Cell Embryonic Stem Cells ...
Perturbation Knockit (Hdh 7/111 CAG)
Disease Huntington
12 Huntington's disease CAG knock-in effect on ... Mus musculus Mus musculus
Cell Cerebellum
Perturbation Knockin (HdhQ111/Q111)
Disease Huntington
13 Huntington's disease CAG knock-in effect on ... Mus musculus Mus musculus
Cell Striatum
Perturbation Knockin (HdhQ111/Q111)
Disease Huntington
14 Huntington disease model: brain striatum (430 2.0) Mus musculus Mus musculus
Cell Striatum
Perturbation YAC128 trangenic
Disease Huntington - 12 months
15 Huntington disease model: brain striatum (430 2.0) Mus musculus Mus musculus
Cell Striatum
Perturbation YAC128 trangenic
Disease Huntington - 24 months
16 Huntington's disease htt-171-82Q in vitro ... Rattus norvegicus Rattus norvegicus
Gene HTT
Cell Striatal neurons
Perturbation htt171-82Q
Disease Huntington
17 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Gene HTT
Cell Brain hemisphere
Perturbation 115 CAG (R6/1 transgenic)
Disease Huntington - 18 weeks
18 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Gene HTT
Cell Brain hemisphere
Perturbation 115 CAG (R6/1 transgenic)
Disease Huntington - 22 weeks
19 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Gene HTT
Cell Brain hemisphere
Perturbation 115 CAG (R6/1 transgenic)
Disease Huntington - 27 weeks
20 Huntington's disease models Mus musculus Mus musculus
Cell Striatum
Perturbation STHdhQ111/Q111
Disease Huntington
21 Moderate stage Huntington's disease lymphocytes Homo sapiens Homo sapiens
Cell Lymphocytes
Disease Huntington - male ...
22 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 3 months
23 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 3.5 months
24 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 10 months
25 Moderate stage Huntington's disease lymphocytes Homo sapiens Homo sapiens
Cell Lymphocytes
Disease Huntington - female ...
26 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 16 months
27 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 4 months
28 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 10 months
29 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum ...
Perturbation Mutant huntingtin ...
Disease Huntington - 8 months
30 Gene expression data from HD mutant and wild ... Rattus norvegicus Rattus norvegicus
Cell ST14A (HD mutant)
Perturbation MIND4 5µM
Disease Huntington
31 Gene expression data from HD mutant and wild ... Rattus norvegicus Rattus norvegicus
Cell ST14A
Perturbation WT vs HD mutant
Disease Huntington
32 Gene expression profile of N171-HD82Q ... Mus musculus Mus musculus
Cell Hippocampus
Perturbation N171HD82Q
Disease Huntington - 10 weeks
33 Gene expression profile of N171-HD82Q ... Mus musculus Mus musculus
Cell Hippocampus
Perturbation N171HD82Q
Disease Huntington - 20 weeks
34 Gene expression profile of N171-HD82Q ... Mus musculus Mus musculus
Cell Cerebellum
Perturbation N171HD82Q
Disease Huntington - 10 weeks
35 Huntington's disease CAG knock-in effect on ... Mus musculus Mus musculus
Gene HTT
Cell Striatum
Perturbation HdhQ111/HdhQ111
Disease Huntington - 3~10 weeks
36 Huntington's disease CAG knock-in effect on ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum
Perturbation HdhQ111/HdhQ111
Disease Huntington - 3~10 weeks
37 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Gene HTT
Cell Embryonic stem cells ...
Perturbation Knockout
Disease Huntington
38 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Gene HTT
Cell Embryonic stem cells ...
Perturbation Knockin (Q20 line)
Disease Huntington
39 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Gene HTT
Cell Embryonic stem cells ...
Perturbation Knockin (Q50 line)
Disease Huntington
40 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Gene HTT
Cell Embryonic stem cells ...
Perturbation Knockin (Q91 line)
Disease Huntington
41 Huntington's disease Hdh knock-out and ... Mus musculus Mus musculus
Gene HTT
Cell Embryonic stem cells ...
Perturbation Knockin (Q111 line)
Disease Huntington
42 In vivo cell-autonomous transcriptional ... Mus musculus Mus musculus
Cell Striatum
Perturbation DE5 (D9N171-98Q) ...
Disease Huntington
43 Striatal gene expression data from ... Mus musculus Mus musculus
Gene CHRDL2
Cell Striatum
Perturbation Q150/Q150 mutant
Disease Huntington - 22 month
44 Striatal gene expression data from 12 ... Mus musculus Mus musculus
Gene HTT
Cell Striatum
Perturbation Hdh4Q80
Disease Huntington - 12 month
45 Striatal gene expression data from 12 ... Mus musculus Mus musculus
Cell Striatum
Perturbation R6/2 transgenic
Disease Huntington - 12 weeks
46 Striatal gene expression data from 12 ... Mus musculus Mus musculus
Cell Striatum
Perturbation R6/2 transgenic
Disease Huntington - 12 weeks ...
47 Moderate stage Huntington's disease lymphocytes Homo sapiens Homo sapiens
Cell Lymphocytes
Disease Huntington - female
48 Moderate stage Huntington's disease lymphocytes Homo sapiens Homo sapiens
Cell Lymphocytes
Disease Huntington - female
49 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Cell Brain hemispheres
Perturbation R6/1 transgenic
Disease Huntington - 27 week
50 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Cell Brain hemispheres
Perturbation R6/1 transgenic
Disease Huntington - 18 week
51 Huntington's disease transgenic model: time course Mus musculus Mus musculus
Cell Brain hemispheres
Perturbation R6/1 transgenic
Disease Huntington - 22 week
52 Striatal gene expression data from 3- and ... Mus musculus Mus musculus
Gene HTT
Cell Striatum
Perturbation HdhQ92/Q92 mutant
Disease Huntington - 18 months
53 Striatal gene expression data from 3- and ... Mus musculus Mus musculus
Gene HTT
Cell Striatum
Perturbation HdhQ92/Q92 mutant
Disease Huntington - 3 months
54 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Cell Cerebellum (A39)
Perturbation 142Q transgenic
Disease Huntington - 10 months
55 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum (x50)
Perturbation 18Q transgenic
Disease Huntington - 16 months
56 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum (A39)
Perturbation 142Q transgenic
Disease Huntington - 4 months
57 Nuclear and extranuclear mutant huntingtin ... Mus musculus Mus musculus
Gene HTT
Cell Cerebellum (S46)
Perturbation 142Q transgenic
Disease Huntington - 10 months