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GEN3VA Reports for these tags

ALS

SOFT file
Title / Description Decrease of Parkin and CD36 expression and body weight correlate with an increase of non-esterified fatty acids in a mouse model for TDP-43 pathology
Accession GSE39585
Summary TDP-43-coding mutations are found among ALS patients. In oder to express human mutant TDP-43 protein in the mouse under the control of the endogenous Tardp promoter, we have generate a mouse line wit 300% elevated TDP-43 level.
Organism Mus musculus
Platform GPL6885
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Gene TARDBP
Cell Brain
Perturbation heterozygote transgenic human mutant TDP43
Disease ALS
Visualizations
Principal Component Analysis
Hierarchical clustering
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA
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Down
Combined