ALS gene signatures (47)

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Title Organism Platform Optional Metadata
1 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - 60 days
2 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - 90 days
3 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - 120 days
4 SOD1-G93A mutant model of amyotrophic lateral ... Rattus norvegicus Rattus norvegicus
Gene SOD1
Cell Embryonic motor neurons
Perturbation G93A mutation
Disease ALS
5 Various muscle diseases (HG-U133B) Homo sapiens Homo sapiens
Cell Skeletal Muscle
Perturbation Normal muscle X ALS ...
Disease ALS
6 SOD1-G93A transgenic model of amyotrophic ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS
7 SOD1-G93A transgenic model of amyotrophic ... Mus musculus Mus musculus
Gene SOD1
Cell Ocular motor neuron
Perturbation G93A mutation
Disease ALS
8 Amyotrophic lateral sclerosis (Lou Gehrig's ... Homo sapiens Homo sapiens
Cell Spinal cord grey matter
Disease Sporadic ALS
9 Amyotrophic lateral sclerosis (Lou Gehrig's ... Homo sapiens Homo sapiens
Cell Spinal cord grey matter
Disease Familial ALS
10 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons
Perturbation G93A mutation
Disease ALS - 60 days
11 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons
Perturbation G93A mutation
Disease ALS - 90 days
12 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons
Perturbation G93A mutation
Disease ALS - 120 days
13 Loss of nuclear TDP-43 in ALS causes altered ... Mus musculus Mus musculus
Gene TARDBP
Cell NSC34, shGFP
Perturbation knockdown (shTardbp)
Disease ALS
14 Loss of nuclear TDP-43 in ALS causes altered ... Mus musculus Mus musculus
Gene TARDBP
Cell NSC34, shLuciferase
Perturbation knockdown (shTardbp)
Disease ALS
15 Gene expression signatures in motor neuron ... Homo sapiens Homo sapiens
Cell Fibroblast
Disease Sporadic ALS
16 Early gene expression changes in spinal cord ... Mus musculus Mus musculus
Gene SOD1
Cell Lumbar spinal cord
Perturbation G93A mutation
Disease ALS - 40 days
17 Early gene expression changes in spinal cord ... Mus musculus Mus musculus
Gene SOD1
Cell Lumbar spinal cord
Perturbation G93A mutation
Disease ALS - 80 days
18 Peripheral blood lymphocytes: ALS patients vs. ... Homo sapiens Homo sapiens
Cell Lymphocytes
Disease Sporadic ALS
19 Evaluation of differential gene expression in ... Homo sapiens Homo sapiens
Cell Skeletal muscle
Disease ALS
20 Transactive response DNA-binding protein ... Homo sapiens Homo sapiens
Gene TARDBP
Cell HEK293E, scrambled siRNA
Perturbation Knockdown
Disease ALS
21 Gene expression profiling of muscles from ... Mus musculus Mus musculus
Gene SOD1
Cell Gastrocnemius
Perturbation G93A mutation
Disease ALS
22 Gene expression profiling of muscles from ... Mus musculus Mus musculus
Gene SOD1
Cell Triceps
Perturbation G93A mutation
Disease ALS
23 Gene expression profiling of muscles from ... Mus musculus Mus musculus
Gene SOD1
Cell Gastrocnemius
Perturbation G93A
Disease ALS
24 Gene expression profiling of muscles from ... Mus musculus Mus musculus
Gene SOD1
Cell Triceps
Perturbation G93A
Disease ALS
25 Transcriptional profile of primary astrocytes ... Rattus norvegicus Rattus norvegicus
Gene SOD1
Cell Astrocytes (Spinal cord)
Perturbation hSOD1G93A mutation
Disease ALS
26 Expression profiling of motor cortex in ... Homo sapiens Homo sapiens
Cell Motor cortex
Disease Sporadic ALS
27 Decrease of Parkin and CD36 expression and ... Mus musculus Mus musculus
Gene TARDBP
Cell Muscle
Perturbation Heterozygote ...
Disease ALS
28 Decrease of Parkin and CD36 expression and ... Mus musculus Mus musculus
Gene TARDBP
Cell Brain
Perturbation heterozygote ...
Disease ALS
29 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A
Disease ALS - 56 days
30 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 56 days
31 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 101 days
32 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 133 days
33 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 111 days
34 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 152 days
35 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 121 days
36 Whole genome transcriptome analysis identifies ... Mus musculus Mus musculus
Gene SOD1
Cell Motor neurons (spinal ...
Perturbation G93A mutation
Disease ALS - 160 days
37 Gene expression analysis of ALS skeletal muscle Homo sapiens Homo sapiens
Cell Skeletal muscle biopsies
Disease ALS
38 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 28
39 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 42
40 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 56
41 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 70
42 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 98
43 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 98
44 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 112
45 Expression data from mutant SOD1(G93A) ... Mus musculus Mus musculus
Gene SOD1
Cell Spinal cord
Perturbation G93A mutation
Disease ALS - Day 126
46 C9ORF72 GGGGCC expanded repeats produce ... Homo sapiens Homo sapiens
Cell Motor neuron
Disease ALS (C9ORF72 mutation)
47 Amyotrophic lateral sclerosis (Lou Gehrig's ... Homo sapiens Homo sapiens
Cell Gray matter
Disease Sporadic ALS