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| Title / Description | Transgenic model of selective ATF6 activation: heart |
| Accession | GDS3667 |
| Summary | Analysis of heart left ventricle from ATF6-MER transgenic (TG) males, treated with tamoxifen to confer activation to ATF6-MER. Activating ATF6 protects the heart of TG animals from endoplasmic reticulum stress. Results provide insight into molecular mechanisms underlying this protective effect. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Cardiac (Mus musculus, left ventricle, nontransgenic) |
| Perturbation | Tamoxifen |
| Disease | Impaired Endoplasmic Reticulum Protein Folding |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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