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GEN3VA Reports for these tags

Melanoma_perturbation

SOFT file
Title / Description Gene expression profiles of Wnt-1 overexpressing melanoma
Accession GSE26656
Summary We aimed to analyze the effects of Wnt-1 overexpression on the mRNA expression profile of human melanoma in a mouse xenograft model and correlated the results with then presence or absence of lymphangiogenesis and metastasis. Affymetrix gene expression analysis revealed activation of canonical and non-canonical targets genes in response to Wnt-1 as compared with controls. In regard to lymphangiogenic factors, the amount of VEGF-C was the single best marker to correlate with the amount of lymph-angiogenesis.
Organism Homo sapiens
Platform GPL570
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Gene WNT1
Cell M24met
Perturbation Overexpression
Disease Melanoma
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA
Up
Down
Combined