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| Title / Description | Gene expression profiles of MCF7 with CARM1 knocked down |
| Accession | GSE26259 |
| Summary | The goal of this study is to identify ERalpha-target genes affected by knocking down of the histone arginine methyltransferase CARM1 in MCF7 breast cancer cells. The roles of CARM1 in ERalpha+ breast cancer was not well characterized. Therefore, we created a Dox inducible CARM1 knockingdown MCF7 cell line where CARM1 is decreased to 20% of endogeneous level to determine the created a Dox-inducible CARM1shRNA overexpressing MCF7 cells for evaluation of the global effects of CARM1 on ERalpha-target gene expression. |
| Organism | Homo sapiens |
| Platform | GPL4133 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell_type | MCF7cells |
| Pert_name | estradiol |
| Pert_id | CHEBI:23965 |
| Organism | human |
| Pert_type | chemical |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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