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| Title / Description | Transcriptomic analysis of folic acid effects in doxorubicin-induced cardiotoxicity |
| Accession | GSE64476 |
| Summary | Doxorubicin (DOXO), a chemotherapeutic drug, is cardiotoxic. We hypothesized that folic acid is an effective therapeutic agent in a mouse model of DOXO-induced cardiotoxicity. We performed genome-wide expression profiling to identify the underlying mechanisms. |
| Organism | Mus musculus |
| Platform | GPL6246 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Heart |
| Cell subtype | Heart - Left ventricle |
| Perturbation | Folic acid |
| Concentration | 10 mg/d |
| Time | for 7 days |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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