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| Title / Description | Gene expression profiles of Wnt-1 overexpressing melanoma |
| Accession | GSE26656 |
| Summary | We aimed to analyze the effects of Wnt-1 overexpression on the mRNA expression profile of human melanoma in a mouse xenograft model and correlated the results with then presence or absence of lymphangiogenesis and metastasis. Affymetrix gene expression analysis revealed activation of canonical and non-canonical targets genes in response to Wnt-1 as compared with controls. In regard to lymphangiogenic factors, the amount of VEGF-C was the single best marker to correlate with the amount of lymph-angiogenesis. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | WNT1 |
| Cell | A375 |
| Perturbation | Overexpression |
| Disease | Melanoma |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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