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| Title / Description | Oral ruxolinitib effect on alopecia areata patients: scalp skin |
| Accession | GDS5275 |
| Summary | Analysis of scalp skin from two alopecia areata (AA) patients treated with oral ruxolitinib for 12 weeks. AA is a T-cell mediated autoimmune disease. Ruxolitinib is a small-molecule inhibitor of the JAK1/2 kinases. Results provide insight into molecular mechanisms underlying the pathogenesis of AA. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Scalp skin |
| Perturbation | Ruxolinitib 12 weeks |
| Disease | Alopecia |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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