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| Title / Description | Imatinib mesylate effect on patient peripheral T-cell lymphomas, not otherwise specified (PTCL/NOS) cells |
| Accession | GDS5405 |
| Summary | Analysis of patient PTCL/NOS cells treated with imatinib mesylate (1uM, 6h). PTCL/NOS tumors are characterized by aberrant expression of platelet-derived growth factor receptor α (PDGFRA). Results provide insight into the molecular effects of inhibiting PDGFRA signaling by imatinib. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | PTCL/NOS cells |
| Perturbation | Imatinib 1 uM - 6 hrs |
| Disease | Peripheral T-cell lymphoma |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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