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| Title / Description | Imatinib mesylate effect on EOL-1 eosinophilic leukemia cell line |
| Accession | GSE53633 |
| Summary | Analysis of EOL-1 cells treated with imatinib mesylate (1uM, 6h). EOL-1 cells carry the platelet derived growth factor receptor α (PDGFRA)/FIP1L1 fusion and exhibit constitutive PDGFRA activation. Results provide insight into the molecular effects of inhibiting PDGFRA signaling by imatinib. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | EOL1 - eosinophilic leukemia cells |
| Perturbation | Imatinib 1 uM - 6 hrs |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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