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| Title / Description | Transactive response DNA-binding protein (TDP-43) knockdown effect on embryonic kidney cells |
| Accession | GSE18632 |
| Summary | Analysis of HEK293E cells depleted of transactive response DNA-binding protein (TDP-43). Inclusions of TDP-43 are hallmarks of frontotemporal dementia and amyotrophic lateral sclerosis (ALS). Results provide insight into the molecular basis of TDP-43 misfunction in neurodegenerative diseases. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | TARDBP |
| Cell | HEK293E, scrambled siRNA |
| Perturbation | Knockdown |
| Disease | ALS |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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