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GEN3VA Reports for these tags

LQTS Clozapine

SOFT file
Title / Description Antipsychotic agents clozapine and haloperidol effects on the brain (I)
Accession GSE6511
Summary Analysis of brains of animals treated for 4 weeks with the atypical antipsychotic clozapine or the typical antipsychotic haloperidol. Clozapine's use as an antipsychotic is limited by agranulocytosis. Results provide insight into the molecular basis of clozapine's therapeutic and toxic effects.
Organism Mus musculus
Platform GPL81
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Cell Right forebrain
Perturbation Clozapine (4 weeks of 12mg/kg/day)
Disease Agranulocytosis, cardiomyopathy
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA
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