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GEN3VA Reports for these tags

LQTS Tamoxifen Knockout

SOFT file
Title / Description Knock out of NOTCH1-bound MYC enhancer (N-Me)
Accession GSE57988
Summary Analysis of Gene Expression in KO mice lacking the NOTCH1-bound MYC putative enhancer located at +1.43K downstream of the MYC gene. Enrichment of MYC signature genes were analyzed by GSEA. Results show that MYC expression signature is indeed significantly enriched.
Organism Mus musculus
Platform GPL6887
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Gene NOTCH1
Cell Lymphoblastic Leukemia Tcell
Perturbation Knockout
Disease Cancer
Visualizations
Principal Component Analysis
Hierarchical clustering
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA
Up
Down
Combined