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| Title / Description | Adrenergic stress effect on transcription factor GATA4 S105A mutants: heart ventricle |
| Accession | GDS3931 |
| Summary | Analysis of heart from Gata4-S105A knock-in mutants (MAPK phosphorylation site at serine 105 mutated to alanine) treated with phenylephrine. The mutants showed a compromised stress response of the myocardium. Results provide insight into molecular basis of stress-related cardiac hypertrophy. |
| Organism | Mus musculus |
| Platform | GPL6246 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Cardiac (Wildtype) |
| Perturbation | Phenylephrine |
| Disease | Cardiac Hypertrophy |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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