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| Title / Description | Lapatinib effect on lapatinib-resistant ErbB2-positive cell line: dose response |
| Accession | GSE38376 |
| Summary | Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib. |
| Organism | Homo sapiens |
| Platform | GPL6947 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | SKBR3 |
| Perturbation | Lapatinib |
| Concentration | 0.1uM |
| Relevant information | Lapatinib sensitive |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
| Up |
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| Down |
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| Combined |
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