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| Title / Description | Effect of ruxolitinib treatment on gene expression in triple-negative breast cancer cell lines |
| Accession | GSE70508 |
| Summary | HCC1143, HCC70, HCC38, and SUM159PT cells were treated for 4 or 24 hrs with 1uM ruxolitinib. Control cells were treated for 24 hrs with DMSO (0.1%). The purpose was to determine changes in gene expresison patterns following inhibition of JAK1/2 in the cells. |
| Organism | Homo sapiens |
| Platform | GPL16686 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | SUM159PT |
| Perturbation | Ruxolitinib |
| Time | 24hrs |
| Concentration | 1uM |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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