| Title | Organism | Platform | |
|---|---|---|---|
| 1 | Huntington disease model: brain striatum (430 2.0) | Mus musculus | Mus musculus |
| 2 | Expression data from 9 and 13 weeks old TIFIAD1Cre mice | Mus musculus | Mus musculus |
| 3 | Striatal gene expression data from 3- and 18-month-old Q92 mice and control mice. | Mus musculus | Mus musculus |
| 4 | Alpha-synuclein deficiency effect on striatum and cerebellum: time course | Mus musculus | Mus musculus |
| 5 | Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration | Mus musculus | Mus musculus |
| 6 | Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration | Mus musculus | Mus musculus |
| 7 | Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration | Mus musculus | Mus musculus |
Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.
Hierarchical clustering of genes based on weights from the differential expression method.
Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.
Hierarchical clustering of enriched terms from
L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.
