ROSIGLITAZONE report

Categorized using metadata field cell

All reports

Gene signatures

Signatures (90) and Custom Report Builder
Title Organism Platform
1 Rosiglitazone effect on PRDM16-deficient inguinal white adipose tissue: stromal-vascular cells Mus musculus Mus musculus
2 Rosiglitazone effect on PRDM16-deficient inguinal white adipose tissue: stromal-vascular cells Mus musculus Mus musculus
3 Rosiglitazone effect on streptozotocin-induced diabetic DBA/2J mice: perpheral sciatic nerve Mus musculus Mus musculus
4 Rosiglitazone effect on streptozotocin-induced diabetic DBA/2J mice: perpheral sciatic nerve Mus musculus Mus musculus
5 Diabetic db/db heart response to rosiglitazone Mus musculus Mus musculus
6 Diabetic db/db heart response to rosiglitazone Mus musculus Mus musculus
7 Thiazolidinedione treatment of 3T3-L1 adipocytes Mus musculus Mus musculus
8 Peroxisome proliferator-activated receptor-gamma target genes in aorta Mus musculus Mus musculus
9 Candidate calorie restriction mimetic drugs effect on the liver Mus musculus Mus musculus
10 PPAR-gamma activation and RAR-alpha inhibition effect on dendritic cells Homo sapiens Homo sapiens
11 Rosiglitazone effect on kidneys Rattus norvegicus Rattus norvegicus
12 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
13 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
14 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
15 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
16 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
17 Peroxisome proliferator-activated receptor gamma 2 activation effect on marrow mesenchymal stem cells: time course Mus musculus Mus musculus
18 Rosiglitazone effect on kidneys Rattus norvegicus Rattus norvegicus
19 Rosiglitazone effect on kidneys Rattus norvegicus Rattus norvegicus
20 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
21 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
22 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
23 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
24 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
25 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
26 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
27 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
28 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
29 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
30 Pharmacology of PPAR isoform agonists on mouse Mus musculus Mus musculus
31 Identification of gene expression changes induced by ligands for RXR and its partners in differentiating human monocyte-derived dendritic cells Homo sapiens Homo sapiens
32 Mechanisms of pparγ activation by non-steroidal anti-inflammatory drugs and GQ16. Mus musculus Mus musculus
33 Mechanisms of pparγ activation by non-steroidal anti-inflammatory drugs and GQ16. Mus musculus Mus musculus
34 SEQC Toxicogenomics Study: microarray data set Rattus norvegicus Rattus norvegicus
35 A systems biology approach to understand the pathophysiological mechanisms of cardiac pathological hypertrophy associated with rosiglitazone Mus musculus Mus musculus
36 Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes Homo sapiens Homo sapiens
37 Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes Homo sapiens Homo sapiens
38 Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes Homo sapiens Homo sapiens
39 Protein sets define disease states and predict in vivo effects of drug treatment Mus musculus Mus musculus
40 LOXs in invasive trophoblasts Homo sapiens Homo sapiens
41 Protein sets define disease states and predict in vivo effects of drug treatment Mus musculus Mus musculus
42 Protein sets define disease states and predict in vivo effects of drug treatment [WAT] Mus musculus Mus musculus
43 Tissue-specific differences in PPARγ control of macrophage function. Mus musculus Mus musculus
44 Tissue-specific differences in PPARγ control of macrophage function. Mus musculus Mus musculus
45 Muscle Involvement in Preservation of Metabolic Flexibility by Treatment using n-3 PUFA, Rosiglitazone, and a combination of both Mus musculus Mus musculus
46 Genome-wide analysis of E157D PPARγ transcriptional activity in NIH-3T3 fibroblasts Mus musculus Mus musculus
47 Genome-wide analysis of E157D PPARγ transcriptional activity in NIH-3T3 fibroblasts Mus musculus Mus musculus
48 PPARγ is a major driver of the accumulation and phenotype of adipose-tissue Treg cells Mus musculus Mus musculus
49 Functional and cellular constraints that shaped the PPARg binding landscape in human and mouse macrophages: human expression Homo sapiens Homo sapiens
50 Functional and cellular constraints that shaped the PPARg binding landscape in human and mouse macrophages: human expression Homo sapiens Homo sapiens
51 Functional and cellular constraints that shaped the PPARg binding landscape in human and mouse macrophages: human expression Homo sapiens Homo sapiens
52 Functional and cellular constraints that shaped the PPARg binding landscape in human and mouse macrophages: human expression Homo sapiens Homo sapiens
53 Functional and cellular constraints that shaped the PPARg binding landscape in human and mouse macrophages: human expression Homo sapiens Homo sapiens
54 PPARg and IL-4-induced gene expression data from wild-type and STAT6 knockout mouse bone marrow-derived macrophages Mus musculus Mus musculus
55 PPARg and IL-4-induced gene expression data from wild-type and STAT6 knockout mouse bone marrow-derived macrophages Mus musculus Mus musculus
56 PPARg and IL-4-induced gene expression data from wild-type and STAT6 knockout mouse bone marrow-derived macrophages Mus musculus Mus musculus
57 PPARg and IL-4-induced gene expression data from wild-type and STAT6 knockout mouse bone marrow-derived macrophages Mus musculus Mus musculus
58 Expression data from human alternatively activated macrophages Homo sapiens Homo sapiens
59 Rosiglitazone-induced molecular changes in adipose progenitors Mus musculus Mus musculus
60 Transcriptome profiling of genes regulated by RXR and its partners in monocyte-derived dendritic cells Homo sapiens Homo sapiens
61 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
62 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
63 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
64 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
65 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
66 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
67 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
68 Cardiac Effects of Rosiglitazone in Male Wistar Rats Rattus norvegicus Rattus norvegicus
69 Genome wide expression analysis of FABP4 modulation in urothelial cancer cell UM-UC14 and UM-UC9 Homo sapiens Homo sapiens
70 The identification of downstream gene of p63, STAT3 and PPAR gamma Homo sapiens Homo sapiens
71 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
72 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
73 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
74 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
75 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
76 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
77 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
78 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
79 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
80 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
81 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
82 Microarray data from murine C3H/10T1/2 and 3T3 L1 adipocytes Mus musculus Mus musculus
83 Liver response to various toxins Rattus norvegicus Rattus norvegicus
84 PPARg regulated gene expression in human dendritic cells Homo sapiens Homo sapiens
85 PPARg regulated gene expression in human dendritic cells Homo sapiens Homo sapiens
86 PPARg regulated gene expression in human dendritic cells Homo sapiens Homo sapiens
87 Gene expression changes in mouse aorta during activation of or interference with PPAR gamma signaling. Mus musculus Mus musculus
88 Gene expression changes in mouse aorta during activation of or interference with PPAR gamma signaling. Mus musculus Mus musculus
89 Gene expression changes in mouse aorta during activation of or interference with PPAR gamma signaling. Mus musculus Mus musculus
90 Gene expression changes in mouse aorta during activation of or interference with PPAR gamma signaling. Mus musculus Mus musculus

PCA

Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.

Genes

Hierarchical clustering of genes based on weights from the differential expression method.

Enrichr

Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.

Hierarchical clustering of enriched terms from

L1000CDS2

L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.