import json, requests
from pprint import pprint
L1000FWD_URL = 'https://maayanlab.cloud/l1000fwd/'
query_string = 'dex'
response = requests.get(L1000FWD_URL + 'synonyms/' + query_string)
if response.status_code == 200:
pprint(response.json())
json.dump(response.json(), open('api1_result.json', 'wb'), indent=4)library(httr)
library(jsonlite)
L1000FWD_URL <- 'https://maayanlab.cloud/l1000fwd/'
query_string <- 'dex'
response <- GET(paste0(L1000FWD_URL, 'synonyms/', query_string))
if (response$status_code == 200){
response <- fromJSON(httr::content(response, 'text'))
print(response)
}[
{
"pert_id": "BRD-K07265709",
"Name": "DEXRAZOXANE"
},
{
"pert_id": "BRD-A93424738",
"Name": "DEXAMETHASONE-ACETATE"
},
{
"pert_id": "BRD-A10188456",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-A35108200",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-A69951442",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-A93424738",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-K38775274",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-K43764301",
"Name": "DEXKETOPROFEN"
},
{
"pert_id": "BRD-K47635719",
"Name": "DEXAMETHASONE"
},
{
"pert_id": "BRD-K04210847",
"Name": "NOLVADEX"
}
]import json, requests
from pprint import pprint
L1000FWD_URL = 'https://maayanlab.cloud/l1000fwd/'
sig_id = 'CPC006_HA1E_24H:BRD-A70155556-001-04-4:40'
response = requests.get(L1000FWD_URL + 'sig/' + sig_id)
if response.status_code == 200:
pprint(response.json())
json.dump(response.json(), open('api2_result.json', 'wb'), indent=4)library(httr)
library(jsonlite)
L1000FWD_URL <- 'https://maayanlab.cloud/l1000fwd/'
sig_id <- 'CPC006_HA1E_24H:BRD-A70155556-001-04-4:40'
response <- GET(paste0(L1000FWD_URL, 'sig/', sig_id))
if (response$status_code == 200){
response <- fromJSON(httr::content(response, 'text'))
print(response)
}{
"pert_time": 24,
"cell_id": "HA1E",
"mean_cosine_dist_centered_by_batch": 0.7235488042208277,
"up_genes": [
"CD74",
"TIMP4",
"ADD3",
"MFGE8",
"FAM3C",
"MMP2",
"SIDT2",
"CASP10",
"PKP4",
"MFAP2",
"S100A11",
"SLC25A16",
"PPL",
"PBXIP1",
"ADIPOQ",
"GSN",
"DCN",
"MRC2",
"SLC39A14",
"DYNLT1",
"DHRS3",
"ARHGEF3",
"MAP3K5",
"PSD3",
"CAPN2",
"CRABP2",
"SOBP",
"TAGLN2",
"PIP4K2A",
"PDE4B",
"ARHGEF40",
"EHBP1L1",
"AQP1",
"TSC22D3",
"B4GALT1",
"FAM69A",
"KCNN4",
"KLHL2",
"PROM1",
"CYP3A5",
"SETD5",
"FGFR3",
"ADCY1",
"SYPL1",
"DNAJA3",
"LRP4",
"RBM47",
"GRB10",
"RNF187",
"TNIK",
"CD9",
"AHR",
"FKBP1B",
"ANGPTL2",
"KDELR2",
"KDELR3",
"XPNPEP1",
"DDAH2",
"AKAP13",
"TNFSF10",
"EVL",
"MTSS1",
"C1ORF38",
"CDKN1C",
"RPL27A",
"DUOX2",
"SERINC3",
"PPFIBP1",
"GFRA1",
"DNM1",
"ABCA8",
"TRIB2",
"LAMB1",
"LTBP3",
"NDRG2",
"RIN2",
"PHLDA1",
"ARL4C",
"EXOSC4",
"KCNJ16",
"PPP1R1A",
"SFN",
"APOD",
"THBS4",
"AKR1C1",
"NID2",
"FAM129A",
"TTN",
"PIK3R1",
"MLPH",
"PJA1",
"ANXA10",
"RRBP1",
"PLIN1",
"EREG",
"TTC3",
"CDC25B",
"EFS",
"GTF2IRD1",
"DSP",
"MLLT11",
"SHB",
"PRKCA",
"ZCCHC24",
"IGFBP5",
"RHOC",
"ITPR3",
"RHOA",
"CAPG",
"PAX8",
"EIF4B",
"OLFML2A",
"HOPX",
"DEPTOR",
"C6ORF62",
"TNS1",
"AZGP1",
"SDC1",
"G6PD",
"SDC4",
"TUBB",
"CALML5",
"CCNI",
"MEF2C",
"MGP",
"ELOVL2",
"SPOCK1",
"GPD1L",
"WNT5A",
"CRIP1",
"FAM134B",
"ATXN1",
"STX1A",
"EPHX1",
"TNFAIP6",
"MKNK2",
"SEC14L1",
"NEB",
"ABCA1",
"SMAD3",
"SLC2A10",
"FABP4",
"RPL37A",
"DLK1",
"MAGT1",
"RHOB",
"TXNIP",
"SVIL",
"ZNF277",
"CDC42SE1",
"LUM",
"CES2",
"AKR1C3",
"LAMC1",
"CYP1B1",
"ASPN",
"TBC1D5",
"IGJ",
"FHL1",
"LINC00341",
"PDCD4",
"REEP5",
"ARMCX3",
"FAM127A",
"TRIL",
"CLIC3",
"POSTN",
"ARL6IP5",
"AIM1",
"ZFP36L1",
"TFF1",
"PLA2G2A",
"A2M",
"SALL1",
"MXRA7",
"TPD52L1",
"NT5DC2",
"FSCN1",
"SLPI",
"KIAA1598",
"NCK2",
"GALNT10",
"ACOX2",
"CFI",
"LRRN3",
"ID1",
"TAPBP",
"MET",
"MAN1C1",
"EMP3",
"COL1A1",
"MMD",
"ZMIZ1",
"PDE4A",
"LDLRAP1",
"ASAP2",
"PRG2",
"TGFB1",
"RPS11",
"DDR1",
"LAPTM4A",
"LAPTM4B",
"PLAUR",
"CD58",
"VCAN",
"JUND",
"IGSF3",
"GPR56",
"ECE1",
"MAGEA3",
"SORBS3",
"SORBS2",
"BIN1",
"HIST1H2AC",
"LOXL1",
"KLF11",
"CDK19",
"RAB31",
"PRDX2",
"NEFL",
"RAB7L1",
"SULF1",
"TATDN2",
"TGOLN2",
"CLIP2",
"KLF2",
"SYNJ2",
"JAG1",
"CTSB",
"ITGAM",
"PLXNB2",
"PDGFC",
"TPST2",
"ANXA4",
"BEX1",
"PTN",
"HOOK2",
"CD44",
"EFHD1",
"PLAU",
"FBN1",
"ABR",
"CYBA",
"TNC",
"CYTH1",
"MEX3D",
"NRP1",
"PBX1",
"COL6A2",
"RNF167",
"NTRK2",
"RPL38",
"ACTN4",
"VAMP8",
"CALR",
"CFB",
"EZR",
"CASP9",
"CREB3L2",
"NOTCH2",
"ADH1B",
"MMP7",
"CRIP2",
"PTPRK",
"AHNAK",
"PITPNC1",
"ABCC3"
],
"batch": "CPC006_HA1E_24H",
"pvalue": 0.0,
"pert_dose": 40.0,
"combined_genes": [
"HSPA2",
"ADD3",
"MFGE8",
"IFI27",
"FAM3C",
"SIVA1",
"IL6ST",
"MFAP2",
"TIMP3",
"THBS1",
"FRY",
"ADIPOQ",
"IL1RL1",
"DCN",
"ACTG2",
"GADD45B",
"PTPLA",
"FAM46A",
"MAP3K5",
"PSD3",
"INHBA",
"ISG15",
"TAGLN2",
"C12ORF24",
"KLHDC10",
"IGF1R",
"SUMO2",
"AQP1",
"CTSB",
"TRIM22",
"SLC25A4",
"B4GALT1",
"FLRT2",
"IFRD2",
"CXCL10",
"CXCL13",
"CYP3A5",
"SETD5",
"FGFR3",
"DNAJA3",
"SNRPD3",
"ADCY1",
"RBM47",
"CCND1",
"GRB10",
"RNF187",
"PPFIBP1",
"AHR",
"FKBP1B",
"ANGPTL2",
"PRSS23",
"IL7R",
"TNFSF10",
"EVL",
"GSPT2",
"CDKN1C",
"RARRES2",
"DUOX2",
"ITGA4",
"CELF2",
"ITGA6",
"MX1",
"PRG2",
"NOP16",
"PTGDS",
"NDRG2",
"RIN2",
"PHLDA1",
"SERPINE1",
"MTSS1",
"PPP1R1A",
"APOD",
"HSPH1",
"AHNAK",
"MEIS2",
"TFRC",
"SOBP",
"TTN",
"PJA1",
"ANXA10",
"PLIN1",
"B4GALT6",
"PDLIM5",
"RSAD2",
"FST",
"TUBB6",
"GBP1",
"EFS",
"DSP",
"TMEM97",
"HERC5",
"PDE4A",
"ZNF589",
"LAMC1",
"ZEB1",
"PAX8",
"CRIM1",
"CR2",
"NAA15",
"DDR1",
"C12ORF5",
"ITGAM",
"GPD1L",
"CRIP1",
"FAM134B",
"EIF4A3",
"ATXN1",
"STX1A",
"RASIP1",
"MKNK2",
"ATF3",
"SEC14L1",
"HERC6",
"SSB",
"ARHGEF3",
"TBX2",
"TNIK",
"EFHD1",
"DLK1",
"AKAP13",
"RHOB",
"CDC42SE1",
"CD9",
"NEDD9",
"JMJD6",
"STAT1",
"PELI2",
"ASPN",
"MMP2",
"IGJ",
"IFI44L",
"FHL1",
"TFPI",
"GALNT3",
"OXTR",
"NDN",
"D4S234E",
"ABCG2",
"MCAM",
"TFF1",
"PLA2G2A",
"SMTN",
"SALL1",
"MXRA7",
"TPD52L1",
"NT5DC2",
"ASRGL1",
"FSCN1",
"SLPI",
"KIAA1598",
"LRP4",
"LRRN3",
"TAPBP",
"HAT1",
"MAN1C1",
"EREG",
"HSPE1",
"COL1A1",
"MME",
"MMD",
"PDE4B",
"LDLRAP1",
"ABCA8",
"CDH11",
"TOX",
"TNFAIP6",
"LAPTM4A",
"LEPREL1",
"LAPTM4B",
"HMGB3",
"PLAUR",
"IGSF3",
"MAP2K3",
"NIP7",
"MOSPD1",
"ERG",
"MAGEA3",
"MAP9",
"BIN1",
"ALDH1A1",
"MID1",
"KLF11",
"CDK19",
"CHORDC1",
"SIK1",
"PRDX2",
"NEFL",
"VPS28",
"RAB7L1",
"SULF1",
"PPL",
"TGOLN2",
"CLIP2",
"RBM25",
"HIST1H2AC",
"SYNJ2",
"TOX3",
"JAG1",
"ATP5G1",
"C1ORF38",
"TPST2",
"ANXA4",
"TXN",
"CD44",
"NOLC1",
"FBN1",
"ABR",
"KLF10",
"DKK1",
"DUSP14",
"MEX3D",
"NRP1",
"TBL1X",
"CRABP2",
"NCK2",
"CFI",
"CALR",
"CFB",
"CYB5A",
"CASP9",
"NOTCH2",
"FAR2",
"EMX2",
"CRIP2",
"ABCC3",
"SFTPD",
"EFNB2",
"TIMP4",
"LUM",
"COL11A1",
"KCNE4",
"SFTPC",
"PPP2R3C",
"KLK10",
"SIDT2",
"CASP10",
"PKP4",
"CDC42EP3",
"PKP2",
"DDX24",
"S100A11",
"SLC25A16",
"BDNF",
"PBXIP1",
"MAFF",
"GSN",
"MRC2",
"NXN",
"SLC39A14",
"TM4SF1",
"DYNLT1",
"DHRS3",
"NTRK2",
"RCAN1",
"GAL",
"SFTPA2",
"CAPN2",
"EDN1",
"LBH",
"MYC",
"PIP4K2A",
"KLF2",
"SH2D1A",
"EHBP1L1",
"PLBD1",
"NME5",
"MRPS7",
"TSC22D3",
"RAMP1",
"TEX10",
"BAZ1A",
"FAM69A",
"KCNN4",
"KLHL2",
"KLK5",
"PROM1",
"KLK7",
"TSPAN8",
"SLC2A10",
"TUFT1",
"SYPL1",
"KCTD12",
"RFX5",
"ACSL5",
"SFN",
"CXCL9",
"GFRA1",
"KDELR2",
"KDELR3",
"TMEM47",
"ABCE1",
"XPNPEP1",
"DDAH2",
"MRTO4",
"CTPS",
"RPL37A",
"C16ORF80",
"RPL27A",
"ATP5L",
"IDO1",
"NUP85",
"SERINC3",
"MYLK",
"PDGFC",
"DNM1",
"TRIB2",
"CLTB",
"LAMB1",
"LTBP3",
"CSDA",
"ARL4C",
"EXOSC4",
"PLXNB2",
"PTN",
"THBS4",
"A2M",
"NID2",
"FAM129A",
"CDC42BPA",
"PIK3R1",
"ZNF277",
"RRBP1",
"GCA",
"TTC3",
"CDC25B",
"CDC25A",
"GTF2IRD1",
"ZCCHC24",
"MLLT11",
"IGFBP3",
"SHB",
"PRKCA",
"IGFBP5",
"RHOC",
"ITPR3",
"RHOA",
"CAPG",
"POLR2I",
"GALNT1",
"EIF4B",
"C10ORF10",
"OLFML2A",
"HOPX",
"DEPTOR",
"POSTN",
"TNS1",
"AZGP1",
"SDC1",
"G6PD",
"SDC4",
"TUBB",
"CALML5",
"CCNI",
"MEF2C",
"ITM2A",
"MGP",
"ELOVL2",
"SPOCK1",
"WNT5A",
"GAS6",
"CD74",
"EPHX1",
"FJX1",
"FILIP1L",
"NEB",
"CYP4B1",
"TPM2",
"STOM",
"FABP4",
"MAGT1",
"PGAM1",
"TXNIP",
"UTP11L",
"AKR1C1",
"AKR1C3",
"CYP1B1",
"NPM1",
"TBC1D5",
"UGT2B17",
"LINC00341",
"PVALB",
"PDCD4",
"CST1",
"REEP5",
"TCF21",
"FAM127A",
"CADM1",
"TGFBR3",
"TRIL",
"CLIC3",
"RRS1",
"ARL6IP5",
"AIM1",
"C6ORF62",
"FERMT2",
"LAMP3",
"NDNF",
"MNAT1",
"ADM",
"TMEM5",
"E2F2",
"HMOX1",
"SERPINB2",
"ACOX2",
"ACOX1",
"IRS2",
"ID1",
"MET",
"CTGF",
"EMP3",
"ODC1",
"DUSP2",
"ALDOC",
"TGFB1",
"RPS11",
"SVIL",
"ARMCX3",
"CD58",
"PRKCQ",
"VCAN",
"JUND",
"MYH10",
"GPR56",
"ECE1",
"SORBS3",
"SORBS2",
"EDNRB",
"CYBA",
"IDH3A",
"LOXL1",
"KIAA0922",
"RAB31",
"IFIT3",
"TATDN2",
"HSPD1",
"IFI44",
"IFIT1",
"ZNF586",
"ZMIZ1",
"HSD11B1",
"RRAGD",
"ABCA1",
"TFAM",
"KCNJ16",
"BEX1",
"ICT1",
"HOOK2",
"TMPRSS3",
"CYR61",
"SRSF7",
"PLAU",
"ZFP36L1",
"SMAD3",
"CES2",
"CALB1",
"TNC",
"CYTH1",
"HEPH",
"CALD1",
"PBX1",
"DDX21",
"COL6A2",
"RNF167",
"GALNT10",
"RPL38",
"ACTN4",
"VAMP8",
"ASAP2",
"SLC16A5",
"EZR",
"FOLR1",
"CREB3L2",
"NEDD4L",
"ADH1B",
"MMP9",
"MMP7",
"MLPH",
"PTPRK",
"LIMCH1",
"PITPNC1",
"ARHGEF40"
],
"pert_id": "BRD-A70155556",
"sig_id": "CPC006_HA1E_24H:BRD-A70155556-001-04-4:40",
"distil_id": [
"CPC006_HA1E_24H_X1.A2_B4_DUO52HI53LO:D24",
"CPC006_HA1E_24H_X1.A2_F1B3_DUO52HI53LO:D24",
"CPC006_HA1E_24H_X1_B3_DUO52HI53LO:D24",
"CPC006_HA1E_24H_X2_B3_DUO52HI53LO:D24",
"CPC006_HA1E_24H_X3_B3_DUO52HI53LO:D24"
],
"down_genes": [
"SFTPD",
"HSPA2",
"TIMP3",
"COL11A1",
"KCNE4",
"SFTPC",
"PPP2R3C",
"IFI27",
"SUMO2",
"SIVA1",
"IL6ST",
"PKP2",
"BDNF",
"CXCL13",
"MAFF",
"IL1RL1",
"NXN",
"ACTG2",
"GADD45B",
"PTPLA",
"FAM46A",
"INHBA",
"SFTPA2",
"EDN1",
"LBH",
"MYC",
"C12ORF24",
"KLHDC10",
"KLK10",
"IGF1R",
"SH2D1A",
"PLBD1",
"KCTD12",
"MRPS7",
"RAMP1",
"TRIM22",
"SLC25A4",
"BAZ1A",
"FLRT2",
"CYP4B1",
"IFRD2",
"KLK7",
"CXCL10",
"TSPAN8",
"SERPINB2",
"TUFT1",
"NME5",
"SNRPD3",
"CCND1",
"RFX5",
"MYLK",
"ACSL5",
"CXCL9",
"HEPH",
"PRSS23",
"TMEM47",
"ABCE1",
"IL7R",
"MRTO4",
"CTPS",
"GSPT2",
"C16ORF80",
"ATP5L",
"ITGA4",
"NUP85",
"ITGA6",
"MX1",
"CLTB",
"CYR61",
"EDNRB",
"CSDA",
"IFIT3",
"SERPINE1",
"IFIT1",
"RSAD2",
"ICT1",
"SRSF7",
"HSPH1",
"LIMCH1",
"MEIS2",
"THBS1",
"TFRC",
"ISG15",
"CDC42BPA",
"CDC25A",
"B4GALT6",
"GCA",
"PDLIM5",
"TMPRSS3",
"TUBB6",
"GBP1",
"TMEM97",
"IGFBP3",
"HERC5",
"HERC6",
"ZNF589",
"SIK1",
"POLR2I",
"GALNT1",
"GALNT3",
"CR2",
"ABCG2",
"NAA15",
"GAS6",
"HAT1",
"HMOX1",
"C12ORF5",
"ITM2A",
"RBM25",
"TOX3",
"EIF4A3",
"SSB",
"EFNB2",
"RASIP1",
"FJX1",
"FILIP1L",
"RCAN1",
"ZNF586",
"TEX10",
"FRY",
"TBX2",
"STOM",
"FST",
"PGAM1",
"NEDD9",
"JMJD6",
"STAT1",
"PELI2",
"NPM1",
"TPM2",
"UTP11L",
"IFI44L",
"UGT2B17",
"TFPI",
"PVALB",
"CST1",
"TCF21",
"DUSP2",
"TGFBR3",
"C10ORF10",
"NDN",
"RRS1",
"MCAM",
"CELF2",
"FERMT2",
"SMTN",
"LAMP3",
"NDNF",
"RARRES2",
"MNAT1",
"ADM",
"TMEM5",
"ACOX1",
"EMX2",
"IRS2",
"CTGF",
"HSPE1",
"OXTR",
"MME",
"CADM1",
"ZEB1",
"CDH11",
"TOX",
"IDO1",
"HMGB3",
"NOP16",
"D4S234E",
"MYH10",
"MAP2K3",
"MOSPD1",
"ERG",
"LEPREL1",
"PTGDS",
"NIP7",
"MAP9",
"ODC1",
"MID1",
"IDH3A",
"TXN",
"KIAA0922",
"CHORDC1",
"VPS28",
"TM4SF1",
"ALDH1A1",
"HSPD1",
"GAL",
"ATP5G1",
"HSD11B1",
"RRAGD",
"TFAM",
"CDC42EP3",
"NOLC1",
"MMP9",
"KLF10",
"CALB1",
"PRKCQ",
"DUSP14",
"ALDOC",
"CALD1",
"DDX21",
"IFI44",
"TBL1X",
"E2F2",
"DDX24",
"SLC16A5",
"CYB5A",
"DKK1",
"NEDD4L",
"ASRGL1",
"FAR2",
"CRIM1",
"FOLR1",
"ATF3",
"KLK5"
],
"pert_desc": "NP-001236"
}| up_genes | Array | An array of strings of gene symbols |
| down_genes | Array | An array of strings of gene symbols |
import json, requests
from pprint import pprint
L1000FWD_URL = 'https://maayanlab.cloud/l1000fwd/'
up_genes = ['KIAA0907','KDM5A','CDC25A','EGR1','GADD45B','RELB','TERF2IP','SMNDC1','TICAM1','NFKB2','RGS2','NCOA3','ICAM1','TEX10','CNOT4','ARID4B','CLPX','CHIC2','CXCL2','FBXO11','MTF2','CDK2','DNTTIP2','GADD45A','GOLT1B','POLR2K','NFKBIE','GABPB1','ECD','PHKG2','RAD9A','NET1','KIAA0753','EZH2','NRAS','ATP6V0B','CDK7','CCNH','SENP6','TIPARP','FOS','ARPP19','TFAP2A','KDM5B','NPC1','TP53BP2','NUSAP1']
down_genes = ['SCCPDH','KIF20A','FZD7','USP22','PIP4K2B','CRYZ','GNB5','EIF4EBP1','PHGDH','RRAGA','SLC25A46','RPA1','HADH','DAG1','RPIA','P4HA2','MACF1','TMEM97','MPZL1','PSMG1','PLK1','SLC37A4','GLRX','CBR3','PRSS23','NUDCD3','CDC20','KIAA0528','NIPSNAP1','TRAM2','STUB1','DERA','MTHFD2','BLVRA','IARS2','LIPA','PGM1','CNDP2','BNIP3','CTSL1','CDC25B','HSPA8','EPRS','PAX8','SACM1L','HOXA5','TLE1','PYGL','TUBB6','LOXL1']
payload = {
'up_genes': up_genes,
'down_genes': down_genes
}
response = requests.post(L1000FWD_URL + 'sig_search', json=payload)
if response.status_code == 200:
pprint(response.json())
json.dump(response.json(), open('api3_result.json', 'wb'), indent=4)library(httr)
library(jsonlite)
L1000FWD_URL <- 'https://maayanlab.cloud/l1000fwd/'
up_genes <- c('KIAA0907','KDM5A','CDC25A','EGR1','GADD45B','RELB','TERF2IP','SMNDC1','TICAM1','NFKB2','RGS2','NCOA3','ICAM1','TEX10','CNOT4','ARID4B','CLPX','CHIC2','CXCL2','FBXO11','MTF2','CDK2','DNTTIP2','GADD45A','GOLT1B','POLR2K','NFKBIE','GABPB1','ECD','PHKG2','RAD9A','NET1','KIAA0753','EZH2','NRAS','ATP6V0B','CDK7','CCNH','SENP6','TIPARP','FOS','ARPP19','TFAP2A','KDM5B','NPC1','TP53BP2','NUSAP1')
down_genes <- c('SCCPDH','KIF20A','FZD7','USP22','PIP4K2B','CRYZ','GNB5','EIF4EBP1','PHGDH','RRAGA','SLC25A46','RPA1','HADH','DAG1','RPIA','P4HA2','MACF1','TMEM97','MPZL1','PSMG1','PLK1','SLC37A4','GLRX','CBR3','PRSS23','NUDCD3','CDC20','KIAA0528','NIPSNAP1','TRAM2','STUB1','DERA','MTHFD2','BLVRA','IARS2','LIPA','PGM1','CNDP2','BNIP3','CTSL1','CDC25B','HSPA8','EPRS','PAX8','SACM1L','HOXA5','TLE1','PYGL','TUBB6','LOXL1')
payload <- list(
up_genes = up_genes,
down_genes = down_genes
)
response <- POST(paste0(L1000FWD_URL, 'sig_search'), body=payload, encode='json')
if (response$status_code == 200){
response <- fromJSON(httr::content(response, 'text'))
print(response)
}{
"result_id": "5a01f822a5d0d538b1b7cb48"
}import json, requests
from pprint import pprint
L1000FWD_URL = 'https://maayanlab.cloud/l1000fwd/'
result_id = '5a01f822a5d0d538b1b7cb48'
response = requests.get(L1000FWD_URL + 'result/topn/' + result_id)
if response.status_code == 200:
pprint(response.json())
json.dump(response.json(), open('api4_result.json', 'wb'), indent=4)library(httr)
library(jsonlite)
L1000FWD_URL <- 'https://maayanlab.cloud/l1000fwd/'
result_id <- '5a01f822a5d0d538b1b7cb48'
response <- GET(paste0(L1000FWD_URL, 'result/topn/', result_id))
if (response$status_code == 200){
response <- fromJSON(httr::content(response, 'text'))
print(response)
}{
"similar": [
{
"scores": 0.5876,
"sig_id": "CPC003_HA1E_24H:BRD-K63606607-001-01-8:10"
},
{
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"sig_id": "CPC003_HA1E_24H:BRD-K35708212-331-03-1:10"
},
{
"scores": 0.4948,
"sig_id": "CPC004_HA1E_24H:BRD-A34806832-001-02-7:10"
},
{
"scores": 0.4845,
"sig_id": "CPC004_HA1E_24H:BRD-A68930007-001-03-1:10"
},
{
"scores": 0.4742,
"sig_id": "CPC004_HA1E_24H:BRD-A94756469-001-03-9:10"
},
{
"scores": 0.4742,
"sig_id": "CPC004_HA1E_24H:BRD-A93236127-001-03-7:10"
},
{
"scores": 0.4433,
"sig_id": "CPC001_HA1E_24H:BRD-K23478508-001-03-7:10"
},
{
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"sig_id": "CPC002_HA1E_24H:BRD-A71459254-001-02-8:10"
},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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"sig_id": "CPC001_HCC515_24H:BRD-K84595254-001-03-0:10"
},
{
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},
{
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},
{
"scores": 0.2784,
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},
{
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},
{
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},
{
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},
{
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"sig_id": "CPC003_HA1E_6H:BRD-K63606607-001-01-8:10"
},
{
"scores": 0.268,
"sig_id": "CPC001_PC3_24H:BRD-K23478508-001-03-7:10"
},
{
"scores": 0.268,
"sig_id": "HOG002_A549_24H:BRD-K76674262-001-02-5:3.33"
},
{
"scores": 0.268,
"sig_id": "CPC001_HA1E_24H:BRD-K84595254-001-03-0:10"
},
{
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},
{
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},
{
"scores": 0.268,
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},
{
"scores": 0.2577,
"sig_id": "CPC014_ASC_24H:BRD-A26002865-001-01-5:10"
},
{
"scores": 0.2577,
"sig_id": "CPC016_A549_6H:BRD-K80348542-001-01-4:10"
},
{
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"sig_id": "CPC004_PC3_24H:BRD-A46747628-001-01-9:10"
},
{
"scores": 0.2577,
"sig_id": "CPC004_HA1E_6H:BRD-A93236127-001-03-7:10"
},
{
"scores": 0.2474,
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},
{
"scores": 0.2474,
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},
{
"scores": 0.2474,
"sig_id": "CPC001_HA1E_6H:BRD-A89434049-001-02-1:10"
},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
"scores": 0.2474,
"sig_id": "CPC015_A549_24H:BRD-A68930007-001-03-1:10"
}
],
"opposite": [
{
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"sig_id": "CPC003_HCC515_6H:BRD-A73909368-001-01-5:10"
},
{
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"sig_id": "CPC004_HCC515_6H:BRD-K43389675-001-01-3:10"
},
{
"scores": -0.1443,
"sig_id": "NMH002_NPC_6H:BRD-K81473043-001-07-0:10"
},
{
"scores": -0.1443,
"sig_id": "CPC011_A549_6H:BRD-K69650333-003-11-6:10"
},
{
"scores": -0.1443,
"sig_id": "CPC018_A375_6H:BRD-K31843556-001-01-7:10"
},
{
"scores": -0.1443,
"sig_id": "CPC004_HCC515_6H:BRD-A52530684-001-01-1:10"
},
{
"scores": -0.1443,
"sig_id": "CPC006_MCF7_24H:BRD-K52075040-001-03-0:44.4"
},
{
"scores": -0.134,
"sig_id": "CPC011_MCF7_6H:BRD-K39484304-001-08-2:10"
},
{
"scores": -0.134,
"sig_id": "CPC009_MCF7_6H:BRD-A68009927-001-02-3:10"
},
{
"scores": -0.1237,
"sig_id": "CPC008_MCF7_6H:BRD-K01896723-001-01-9:10"
},
{
"scores": -0.1237,
"sig_id": "CPC014_HCC515_6H:BRD-M16762496-001-01-9:10"
},
{
"scores": -0.1237,
"sig_id": "CPC004_HCC515_6H:BRD-K04548931-003-05-8:10"
},
{
"scores": -0.1237,
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},
{
"scores": -0.1237,
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},
{
"scores": -0.1134,
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},
{
"scores": -0.1134,
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
"scores": -0.1134,
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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{
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{
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},
{
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},
{
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},
{
"scores": -0.0928,
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},
{
"scores": -0.0928,
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},
{
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},
{
"scores": -0.0928,
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},
{
"scores": -0.0928,
"sig_id": "CPC018_HT29_6H:BRD-K62810658-001-08-0:10"
},
{
"scores": -0.0928,
"sig_id": "CPC008_VCAP_6H:BRD-K99530743-001-01-3:10"
}
]
}