Interaction network and enrichment analysis of genes upregulated in Neurological pain disorder
Canned Analysis
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General Information
AccessionDCA00032928
TitleInteraction network and enrichment analysis of genes upregulated in Neurological pain disorder
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Neurological pain disorder and healthy control cells in the Dorsal Root Ganglia cell type.
Analysis URLhttp://genemania.org/#/search/rat/Cacna2d1|Gap43|Tubb2b|Acta1|Vim|Lyz2|Fabp5|Pabpc4|Col1a2|Tuba1b|Cd74|LOC501503|COX3|Rpl26|Ubc|Fstl1|Rps6|RT1-Da|LOC100134871|Atf3|Vgf|Myh2|Rpl22|LOC100360413|Rplp0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:129
Cell TypeDorsal Root Ganglia
Disease NameNeurological pain disorder
Organismrat
UMLS CUIC0423704
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM50750, GSM50751, GSM50752, GSM50753, GSM50754, GSM50755, GSM50756
Perturbed SamplesGSM50737, GSM50738, GSM50739, GSM50740, GSM50741, GSM50742, GSM50743, GSM50744, GSM50745, GSM50746, GSM50747, GSM50748, GSM50749
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2636
Gene Expression Omnibus
Peripheral nerve injury effect on dorsal root ganglion: time course
7
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