Peripheral nerve injury effect on dorsal root ganglion: time course
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE2636
TitlePeripheral nerve injury effect on dorsal root ganglion: time course
DescriptionAnalysis of lumbar dorsal root ganglia at various time points up to 50 days following peripheral nerve injury inflicted by either partial sciatic nerve ligation or chronic constriction. Results provide insight into the molecular mechanisms underlying neuropathic pain.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2636
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Geneset

Interaction network and enrichment analysis of genes downregulated in Neurological pain disorder
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in Neurological pain disorder
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Small molecules which mimic Neurological pain disorder
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Neurological pain disorder
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in Neurological pain disorder
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes downregulated in Neurological pain disorder
An enrichment analysis was performed on the top 500 most downregulated genes identified by...
Enrichment analysis of genes upregulated in Neurological pain disorder
An enrichment analysis was performed on the top 500 most upregulated genes identified by a...
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