Interaction network and enrichment analysis of genes downregulated in myocardial infarction
Canned Analysis
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General Information
AccessionDCA00033101
TitleInteraction network and enrichment analysis of genes downregulated in myocardial infarction
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by myocardial infarction and healthy control cells in the Myocardial tissue cell type.
Analysis URLhttp://genemania.org/#/search/rat/Atp5a1|Gad1|Fabp3|Acadvl|Rab3b|Nppc|Cyp4f4|Kcnb1|Pfkm|Atp2a2|Scn2a|Ppm1b|Gapdh|Gnb3|Crip2|Meox2|Rab12|Snap25|Scn1b|Gna12|Gnas|Sod1|Aldoa|Cox8b|Cyct
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:200
Cell TypeMyocardial tissue
DO IDDOID:5844
Disease Namemyocardial infarction
Organismrat
UMLS CUIC0027051
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM34956, GSM34962, GSM34963, GSM34964, GSM34965, GSM34966, GSM34967, GSM34983, GSM34984, GSM34985, GSM34986, GSM34987
Perturbed SamplesGSM34950, GSM34951, GSM34952, GSM34953, GSM34954, GSM34955, GSM34971, GSM34972, GSM34973, GSM34974, GSM34975, GSM34976
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1957
Gene Expression Omnibus
Congestive heart failure model
7
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