Interaction network and enrichment analysis of genes downregulated in adrenoleukodystrophy
Canned Analysis
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General Information
AccessionDCA00034153
TitleInteraction network and enrichment analysis of genes downregulated in adrenoleukodystrophy
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by adrenoleukodystrophy and healthy control cells in the Primary dermal fibroblasts (Childhood cerebral adrenoleukodystrophy) cell type.
Analysis URLhttp://genemania.org/#/search/human/S100A4|ADM|GAPDH|CAV1|WISP2|DCAF6|CLEC3B|COX2|LDHA|LGALS1|LUM|ENPP2|GAS6|GJA1|HLA-B|UBC|IFITM3|IGFBP4|PKM|MYL9|SH3KBP1|AKR1C3|THY1|SH3BGRL3|COX1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:709
Cell TypePrimary dermal fibroblasts (Childhood cerebral adrenoleukodystrophy)
DO IDDOID:10588
Disease Nameadrenoleukodystrophy
Organismhuman
UMLS CUIC0162309
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM847078, GSM847079, GSM847080, GSM847081, GSM847082
Perturbed SamplesGSM847083, GSM847084, GSM847085, GSM847086, GSM847087
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE34308
Gene Expression Omnibus
Childhood cerebral adrenoleukodystrophy: primary dermal fibroblasts
7
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