Interaction network and enrichment analysis of genes downregulated in acute myocarditis
Canned Analysis
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General Information
AccessionDCA00034329
TitleInteraction network and enrichment analysis of genes downregulated in acute myocarditis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by acute myocarditis and healthy control cells in the Heart (from CVB3-infected females - day 10 postinfection) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ech1|Cox7a1|Gsn|Cox8b|Acadm|Idh2|Hadhb|Acaa2|Rn28s1|Lpl|Hadha|Nnt|Uqcrc1|Mt1|Cd36|Ogdh|Etfdh|Crip2|Hadh|Cox6c|Aqp1|Pln|Mdh2|Slc25a4|Fabp3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:802
Cell TypeHeart (from CVB3-infected females - day 10 postinfection)
DO IDDOID:3951
Disease Nameacute myocarditis
Organismmouse
UMLS CUIC0155686
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM863110, GSM863111, GSM863112
Perturbed SamplesGSM863116, GSM863117, GSM863118
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE35182
Gene Expression Omnibus
Sex effect on chronic coxsackievirus B3-induced myocarditis: heart
7
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