Interaction network and enrichment analysis of genes upregulated in H3F3A Mutation (K27M - mutation of key residues in histone H3.3)
Canned Analysis
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General Information
| Accession | DCA00036744 |
| Title | Interaction network and enrichment analysis of genes upregulated in H3F3A Mutation (K27M - mutation of key residues in histone H3.3) |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between H3F3A Mutation (K27M - mutation of key residues in histone H3.3) cells and control cells in the Pediatric glioblastoma (GBM) tumors cell type. |
| Analysis URL | http://genemania.org/#/search/human/BCHE|SH3KBP1|SPARCL1|HTRA1|PTN|SPARC|DBI|PMP2|TMSB10|TIMP1|TUBB2A|LGALS1|FTH1P5|PTPRZ1|IL13RA2|TENM2|COX2|ROBO1|ID2|TMSB4XP8|C11orf96|OLIG1|CPE|HIST1H4C|TUBA1A |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | cadimo |
| CREEDS ID | gene:1229 |
| Cell Type | Pediatric glioblastoma (GBM) tumors |
| Gene Symbol (human) | H3F3A |
| Organism | human |
| Perturbation Type | Mutation (K27M - mutation of key residues in histone H3.3) |
Characteristic Direction parameters
| Gene Set | upregulated |
| Gene Set Size | 50 |
| Control Samples | GSM855946, GSM855948, GSM855949, GSM855950, GSM855951, GSM855952, GSM855953, GSM855954, GSM855955, GSM855956, GSM855958, GSM855959, GSM855960, GSM855961, GSM855962, GSM855963, GSM855964, GSM855965 |
| Perturbed Samples | GSM855947, GSM855957, GSM855966, GSM855967, GSM855968 |
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