Interaction network and enrichment analysis of genes downregulated in TSC1 Deficiency
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039587
TitleInteraction network and enrichment analysis of genes downregulated in TSC1 Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between TSC1 Deficiency cells and control cells in the Naïve CD8 T cells cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rpl22l1|Fos|Cytip|Snora81|Ddx5|Rpl12|Dgka|Dusp1|Hnrnph1|Eif1|Ptprc|Zfp36l2|Npm1|Cnbp|Rps18|Stk17b|Rps15|Clk1|Rpl7a|Rps5|Rpl18a|Trav9d-3|Tuba1b|Actg1|Rpl10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:374
Cell TypeNaïve CD8 T cells
Gene Symbol (human)TSC1
Gene Symbol (mouse)Tsc1
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM738381, GSM738382
Perturbed SamplesGSM738383, GSM738384
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29797
Gene Expression Omnibus
Tuberous sclerosis complex 1 deficient nave CD4 and CD8 T cells
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.