Myotube starvation model of atrophy
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE1776
TitleMyotube starvation model of atrophy
DescriptionExpression profiling of starved skeletal muscle C2C12 myotubes. Starvation induced by witholding differentiation medium containing 2%% horse serum for 4 days. Results show that the expression profile of starved myotubes differs to that of whole muscle atrophy.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1776
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Geneset

Interaction network and enrichment analysis of genes downregulated in Nutritional deficiency, NEC
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in Nutritional deficiency, NEC
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Small molecules which mimic Nutritional deficiency, NEC
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Nutritional deficiency, NEC
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in Nutritional deficiency, NEC
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes downregulated in Nutritional deficiency, NEC
An enrichment analysis was performed on the top 500 most downregulated genes identified by...
Enrichment analysis of genes upregulated in Nutritional deficiency, NEC
An enrichment analysis was performed on the top 500 most upregulated genes identified by a...
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