Expression data from mock- or LMO3 silenced differentiating adipose stem cells
Transcriptomics Dataset
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General Information
AccessionGSE41712
TitleExpression data from mock- or LMO3 silenced differentiating adipose stem cells
DescriptionIn this study we aimed to gain further insight on the role of GCs in adipocyte differentiation. For the future drugability of candidate targets it is of utmost importance to find factors relevant to human biology. Thus, we analyzed the transcriptome of GC induced primary human adipose stem cells (hASC) to identify novel factors downstream of GC action We used microarrays to detail the global programme of gene expression following glucocorticoid treatment and identified distinct classes of up- and downregulated genes during this process.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE41712
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMO3 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in LMO3 KD
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in LMO3 KD
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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