General Information
| Description | Simultaneous visual analysis of orthologs and their interaction neighborhoods across different organisms |
| Homepage | http://wodaklab.org/orthonets/ |
Publications
OrthoNets: simultaneous visual analysis of orthologs and their interaction neighborhoods across different organisms
Motivation:
Protein interaction networks contain a wealth of biological information, but their large size often hinders cross-organism comparisons. We present OrthoNets, a Cytoscape plugin that displays protein–protein interaction (PPI) networks from two organisms simultaneously, highlighting orthology relationships and aggregating several types of biomedical annotations. OrthoNets also allows PPI networks derived from experiments to be overlaid on networks extracted from public databases, supporting the identification and verification of new interactors. Any newly identified PPIs can be validated by checking whether their orthologs interact in another organism.
Availability:
OrthoNets is freely available at http://wodaklab.org/orthonets/.
Contact:
jim.vlasblom@utoronto.ca
Related Tools
PIE the search
Published December 2011
Searching PubMed literature for protein interaction information
NCMine
Published July 2016
Core-peripheral based functional module detection using near-clique mining
Path2PPI
Published January 2016
An R package to predict protein–protein interaction networks for a set of proteins
RedNemo
Published November 2016
Topology-based PPI network reconstruction via repeated diffusion with neighborhood modifications
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
