General Information
| Description | A tool for associating genes with diseases via network propagation |
| Homepage | http://www.cs.tau.ac.il/~bnet/software/PrincePlugin/ |
Publications
PRINCIPLE: a tool for associating genes with diseases via network propagation
Summary:
PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein–protein interaction network to genes causing phenotypically similar disorders to the query disease.
Availability:
Implemented in Java, PRINCIPLE runs over Cytoscape 2.7 or newer versions. Binaries, default input files and documentation are freely available at http://www.cs.tau.ac.il/~bnet/software/PrincePlugin/.
Contact:
roded@tau.ac.il; assafgot@tau.ac.il
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