This is a permanent results page for your analyzed data. Please save the link in your browser's address bar.
| Title / Description | Heart response to isocitrate dehydrogenase 2 mutations IDH2R140Q and IDH2R172K |
| Accession | GDS4893 |
| Summary | Analysis of hearts from transgenics with conditionally-activated isocitrate dehydrogenase 2 mutant (IDH2) R140Q and R172K alleles. Mutant IDH2 causes cardiomyopathy and neurodegeneration. Results provide insight into molecular mechanisms underlying the cardiac defects associated with IDH2 mutations. |
| Organism | Mus musculus |
| Platform | GPL6246 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | heart |
| Perturbation | isocitrate dehydrogenase 2 R172K mutant |
| Disease | cardiomyopathy |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
| Up |
|
|||
| Down |
|
|||
| Combined |
|
|
|
