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| Title / Description | Liver response to a metformin supplemented high fat diet deficient in methionine and choline |
| Accession | GSE35961 |
| Summary | Analysis of livers of animals fed a methionine- and choline- deficient, high fat diet (MCD+HF) containing metformin. MCD+HF models non-alcoholic steatohepatitis (NASH). Results provide insight into the feasibility of using metformin, an anti-diabetic drug, to treat NASH without underlying diabetes. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Metformin |
| Smiles | CN(C)C(=N)N=C(N)N |
| Drugbank_id | DB00331 |
| Pubchem_cid | 4091 |
| Cell_type | liver |
| Organism | mouse |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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