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| Title / Description | Dopaminergic transcription factors Ascl1, Lmx1a, Nurr1 combined effect on embryonic fibroblasts |
| Accession | GDS4155 |
| Summary | Analysis of induced dopaminergic (iDA) neurons generated from E14.5 mouse embryonic fibroblasts (MEFs) reprogrammed by infection with lentiviruses expressing dopaminergic transcription factors Ascl1, Lmx1a and Nurr1. Results provide insight into the molecular basis of MEF to iDA reprogramming. |
| Organism | Mus musculus |
| Platform | GPL6246 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Mouse embryonic fibroblast (MEF) |
| Perturbation | Reprogramming to iDA neuron using Ascl1, Lmx1a and Nurr1 |
| Disease | PD |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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