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| Title / Description | PLK1 signaling coopereates with estrogen receptor-dependent gene transcription. |
| Accession | GSE46856 |
| Summary | Analysis of MCF7 breast cancer cells treated with estadiol for 6 h in presence or absence of the specific PLK1 inhibitor BI2536. Together with CHIP and global phosphoproteome data, the results demonstrate a key role of PLK1 in the estrogen receptor-mediated gene response. |
| Organism | Homo sapiens |
| Platform | GPL13497 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell_type | MCF7cells |
| Pert_name | estradiol |
| Pert_id | PubChemCID:5757 |
| Organism | human |
| Pert_type | chemical |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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