Severe pandemic H1N1 influenza effect on peripheral blood: time course
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE27131
TitleSevere pandemic H1N1 influenza effect on peripheral blood: time course
DescriptionTemporal analysis of peripheral blood from patients with severe pdm(H1N1) influenza, bilateral chest infiltrates, and in need of mechanical ventilation, but without significant co-morbidity. Results provide insight into molecular basis of immune responses in patients with severe pdmH1N1 infection.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27131
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Geneset

Interaction network and enrichment analysis of genes downregulated in swine influenza
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in swine influenza
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Small molecules which mimic swine influenza
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse swine influenza
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in swine influenza
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes downregulated in swine influenza
An enrichment analysis was performed on the top 500 most downregulated genes identified by...
Enrichment analysis of genes upregulated in swine influenza
An enrichment analysis was performed on the top 500 most upregulated genes identified by a...
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