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| Title / Description | Gene expression profile in melanomas from Pdk1-inactivated BrafV600E::Pten-/- mice |
| Accession | GSE42187 |
| Summary | Gene expression profiling was performed to access the changes in gene expression in melanomas from Pdk1-inactivated Brafv600E::Pten-/- mice. The expression profiles of the BrafV600E::Pten-/-::Pdk1-/- were compared to the BrafV600E::Pten-/-::Pdk+/+ genotypes. The analysis has identified several important signaling pathways in Pdk1-dependent melanomagenesis. |
| Organism | Mus musculus |
| Platform | GPL6885 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | PDK1 |
| Cell | BrafV600E (Pten/-::Pdk1+/+) |
| Perturbation | Knockout |
| Disease | Melanoma |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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| Combined |
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