LIGANDS_BD2K_LINCS_DCIC_COURSERA report

Categorized using metadata field ligand_name

All reports

Gene signatures

Signatures (275) and Custom Report Builder
Title Organism Platform
1 Growth hormone effect on adipocytes: time course Mus musculus Mus musculus
2 Growth hormone effect on adipocytes: time course Mus musculus Mus musculus
3 Cyclin D1 determines estrogen depependent signaling in mouse mammary gland. Mus musculus Mus musculus
4 Cyclin D1 determines estrogen depependent signaling in mouse mammary gland. Mus musculus Mus musculus
5 Changes in gene expression upon co-treatment of cells with Dex and E2 Mus musculus Mus musculus
6 GENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE Mus musculus Mus musculus
7 GENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE Mus musculus Mus musculus
8 Growth hormone effect on adipocytes: time course Mus musculus Mus musculus
9 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
10 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
11 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
12 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
13 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
14 The transcriptional response of mouse uterus to estrogen is genetically regulated Mus musculus Mus musculus
15 Transcriptomal effects of four-day exposure to estradiol on mouse primary culture urogenital sinus mesenchymal cells of fetal mouse prostate Mus musculus Mus musculus
16 Transcriptomal effects of four-day exposure to estradiol on mouse primary culture urogenital sinus mesenchymal cells of fetal mouse prostate Mus musculus Mus musculus
17 mRNA expression data from mice infected with H. pylori treated with estradiol, tamoxifen, or placebo Mus musculus Mus musculus
18 Human endothelial gene expression under estradiol and oxLDL treatments Homo sapiens Homo sapiens
19 Insulin-like growth factor-I effect on breast cancer cell line: time course Homo sapiens Homo sapiens
20 Differential effects of progesterone and medroxyprogesterone acetate on normal breast cells Homo sapiens Homo sapiens
21 Gene expression profiles of MCF-7 cells treated with Si-Wu-Tang, estradiol and ferulic acid Homo sapiens Homo sapiens
22 In vitro pineal gland organ culture response to adrenergic/cAMP stimulation (Expt. C) Rattus norvegicus Rattus norvegicus
23 Estrogen or insulin-like growth factor I stimulated MCF-7 breast cancer cells: time course Homo sapiens Homo sapiens
24 Estrogen or insulin-like growth factor I stimulated MCF-7 breast cancer cells: time course Homo sapiens Homo sapiens
25 Estrogen or insulin-like growth factor I stimulated MCF-7 breast cancer cells: time course Homo sapiens Homo sapiens
26 Estrogen or insulin-like growth factor I stimulated MCF-7 breast cancer cells: time course Homo sapiens Homo sapiens
27 Potential mechanisms of endocrine disruptors as revealed by uterine gene profile Mus musculus Mus musculus
28 Insulin-like growth factor-I effect on breast cancer cell line: time course Homo sapiens Homo sapiens
29 Potential mechanisms of endocrine disruptors as revealed by uterine gene profile Mus musculus Mus musculus
30 Interleukin-10 effect on peripheral blood mononuclear cells Homo sapiens Homo sapiens
31 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
32 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
33 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
34 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
35 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
36 Microarray analysis adherent peripheral blood mononuclear cells stimulated with IL-10, IL-15, and IL-4 Homo sapiens Homo sapiens
37 Uterine Gene Profile of Estriol, a Weak Estrogen Mus musculus Mus musculus
38 Uterine Gene Profile of Estriol, a Weak Estrogen Mus musculus Mus musculus
39 TGF-beta1 effect on renal mesangial cells Mus musculus Mus musculus
40 Uterine Gene Profile of Estriol, a Weak Estrogen Mus musculus Mus musculus
41 Uterine Gene Profile of Estriol, a Weak Estrogen Mus musculus Mus musculus
42 Expression data from estradiol-treated fetal urogenital sinus mesenchyme cells Mus musculus Mus musculus
43 Estrogen- and Myc-regulated genes in MCF-7 breast cancer cells Homo sapiens Homo sapiens
44 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
45 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
46 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
47 Uterine response to physiologic, plant-derived, and synthetic estrogen Mus musculus Mus musculus
48 Testosterone-induced persistent dysregulations and transdifferentiation to exocrine pancreas in the female liver Mus musculus Mus musculus
49 Testosterone-induced persistent dysregulations and transdifferentiation to exocrine pancreas in the female liver Mus musculus Mus musculus
50 Transforming growth factor beta effect on Panc-1 pancreatic adenocarcinoma cell line Homo sapiens Homo sapiens
51 Expression data from MCF-7aro aromatase inhibitor-resistant, tamoxifen-resistant and LTEDaro lines. Homo sapiens Homo sapiens
52 Gene expression analyses of PR action in the uteri of SRC-2 mutant mice Mus musculus Mus musculus
53 Gene expression analyses of PR action in the uteri of SRC-2 mutant mice Mus musculus Mus musculus
54 Breast adenocarcinoma MCF-7 cell line response to 27-Hydroxycholesterol and estradiol Homo sapiens Homo sapiens
55 Methylmalonic acidemia-associated renal disease model: kidney Mus musculus Mus musculus
56 CD34+derived erythoblast co-culture with Plasmodium falciparum 3D7 (GenePattern analysis) Homo sapiens Homo sapiens
57 Erythroid progenitor erythropoiesis Mus musculus Mus musculus
58 Multiple sclerosis and vitamin D Mus musculus Mus musculus
59 Polycystic ovary syndrome: proliferative phase endometrial cell types Homo sapiens Homo sapiens
60 Cerebellar neuronal cell response to thyroid hormone: time course Mus musculus Mus musculus
61 Transforming growth factor-beta effect on Hepatocellular carcinoma Huh-7 cell line Homo sapiens Homo sapiens
62 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
63 Growth hormone effect on adipocytes: time course Mus musculus Mus musculus
64 IL-17C effect on keratinocytes: time course Homo sapiens Homo sapiens
65 Interleukin-17A effect on primary airway smooth muscle cells from asthmatics Homo sapiens Homo sapiens
66 IL-17C effect on keratinocytes: time course Homo sapiens Homo sapiens
67 Interleukin-17A effect on primary airway smooth muscle cells from asthmatics Homo sapiens Homo sapiens
68 Primary keratinocyte response to in vitro cytokine exposure Homo sapiens Homo sapiens
69 Primary keratinocyte response to in vitro cytokine exposure Homo sapiens Homo sapiens
70 Primary keratinocyte response to in vitro cytokine exposure Homo sapiens Homo sapiens
71 Primary hepatocyte response to interferon-α or interleukin 28B: time course Homo sapiens Homo sapiens
72 Transforming growth factor-β effect on fibroblasts in the presence of Trypanosoma cruzi conditioned medium Homo sapiens Homo sapiens
73 Primary keratinocyte response to in vitro cytokine exposure Homo sapiens Homo sapiens
74 Primary hepatocyte response to interferon-α or interleukin 28B: time course Homo sapiens Homo sapiens
75 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
76 Primary hepatocyte response to interferon-α or interleukin 28B: time course Homo sapiens Homo sapiens
77 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
78 Primary keratinocyte response to in vitro cytokine exposure Homo sapiens Homo sapiens
79 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
80 All-trans-retinoic acid effect on transglutaminase 2-silenced, NB4 model of acute promyelocytic leukemia: time course Homo sapiens Homo sapiens
81 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
82 Primary hepatocyte response to interferon-α or interleukin 28B: time course Homo sapiens Homo sapiens
83 Neuromedin U effect on type-2 Th cells: time course Mus musculus Mus musculus
84 All-trans-retinoic acid effect on transglutaminase 2-silenced, NB4 model of acute promyelocytic leukemia: time course Homo sapiens Homo sapiens
85 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
86 1,25 dihydroxyvitamin D effect on prostate epithelial cell line RWPE1: time course Homo sapiens Homo sapiens
87 All-trans-retinoic acid effect on transglutaminase 2-silenced, NB4 model of acute promyelocytic leukemia: time course Homo sapiens Homo sapiens
88 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
89 1,25 dihydroxyvitamin D effect on prostate epithelial cell line RWPE1: time course Homo sapiens Homo sapiens
90 All-trans-retinoic acid effect on transglutaminase 2-silenced, NB4 model of acute promyelocytic leukemia: time course Homo sapiens Homo sapiens
91 Interleukin-12 effect on peripheral blood mononuclear cells (HG-U133B) Homo sapiens Homo sapiens
92 Bronchial epithelial cells response to interleukin-22 and interleukin-17 Homo sapiens Homo sapiens
93 Bronchial epithelial cells response to interleukin-22 and interleukin-17 Homo sapiens Homo sapiens
94 Neuromedin U effect on type-2 Th cells: time course Mus musculus Mus musculus
95 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
96 1,25 dihydroxyvitamin D effect on prostate epithelial cell line RWPE1: time course Homo sapiens Homo sapiens
97 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
98 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
99 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
100 Interleukin-13 effect on esophageal epithelial cells from eosinophilic esophagitis patients Homo sapiens Homo sapiens
101 Interleukin 1β effect on insulinoma cell line overexpressing pancreatic duodenum homeobox 1: time course Rattus norvegicus Rattus norvegicus
102 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
103 TRIF-deficient Herpes simplex encephalitis patient: fibroblast response to interleukin-1β and TLR3 agonist poly (I:C) Homo sapiens Homo sapiens
104 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
105 Neuromedin U effect on type-2 Th cells: time course Mus musculus Mus musculus
106 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
107 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
108 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
109 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
110 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
111 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
112 Cytotoxic T cell line response to interleukin-2: time course Mus musculus Mus musculus
113 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
114 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
115 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
116 Neuromedin U effect on type-2 Th cells: time course Mus musculus Mus musculus
117 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
118 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
119 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
120 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
121 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
122 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
123 Human endometrial cancer cell gene expression profiles of the estrogen receptor α (ERα) hinge region mutants (H1 and H2NES) Homo sapiens Homo sapiens
124 Interleukin-1 effect on epidermal keratinocytes: time course Homo sapiens Homo sapiens
125 Glucosamine and interleukin-1 beta effect on chondrocytes Rattus norvegicus Rattus norvegicus
126 IL-21 and IL-15 synergistic effect on naïve CD8+ T cells Mus musculus Mus musculus
127 Inflammatory amnion mesenchymal cell model response to interleukin-1β: time course Homo sapiens Homo sapiens
128 Macrophage response to IL-6, and SOCS3 effect Mus musculus Mus musculus
129 IL-21 and IL-15 synergistic effect on naïve CD8+ T cells Mus musculus Mus musculus
130 Macrophage response to IL-6, and SOCS3 effect Mus musculus Mus musculus
131 Macrophage response to IL-6, and SOCS3 effect Mus musculus Mus musculus
132 Macrophage response to IL-6, and SOCS3 effect Mus musculus Mus musculus
133 Development of gene expression signatures for mouse macrophages polarization Mus musculus Mus musculus
134 Examination of IL-12 and IL-33 or IL-12 + IL-33 induced mRNA in effector CD8 T cells Mus musculus Mus musculus
135 Examination of IL-12 and IL-33 or IL-12 + IL-33 induced mRNA in effector CD8 T cells Mus musculus Mus musculus
136 Integrated miRNA and gene expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation [gene] Homo sapiens Homo sapiens
137 The immunomodulatory effects of soluble receptor of activated nuclear factor kappa ligand (sRANKL) on monocyte-derived macrophages Homo sapiens Homo sapiens
138 Inflammatory amnion mesenchymal cell model response to interleukin-1β: time course Homo sapiens Homo sapiens
139 Integrated miRNA and gene expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation [gene] Homo sapiens Homo sapiens
140 Expression data from primary culture human myometrial cells Homo sapiens Homo sapiens
141 Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis Homo sapiens Homo sapiens
142 Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis Homo sapiens Homo sapiens
143 TGFβ inhibitor effect on induced cardiomyocytes Mus musculus Mus musculus
144 TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ Homo sapiens Homo sapiens
145 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
146 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
147 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
148 Anti-Mullerian hormone effect on ovary Rattus norvegicus Rattus norvegicus
149 Estrogen effect on estrogen receptors alpha and beta single knockouts: aorta Mus musculus Mus musculus
150 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
151 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
152 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
153 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
154 TGF-beta-induced epithelial-mesenchymal transition model Homo sapiens Homo sapiens
155 TGF-beta 1 effect on immortalized ovarian surface epithelial cell line: time course Homo sapiens Homo sapiens
156 TGF-beta 1 effect on immortalized ovarian surface epithelial cell line: time course Homo sapiens Homo sapiens
157 TGF-beta 1 effect on immortalized ovarian surface epithelial cell line: time course Homo sapiens Homo sapiens
158 Estradiol effect on breast cancer cell line in the absence of protein synthesis Homo sapiens Homo sapiens
159 Estradiol effect on breast cancer cell line in the absence of protein synthesis Homo sapiens Homo sapiens
160 Estrogen effect on estrogen receptors alpha and beta single knockouts: aorta Mus musculus Mus musculus
161 Abdominal Aortic Aneurysm in the ApoE Knockout Mouse: Time Course of Control vs. Angiotensin II Mus musculus Mus musculus
162 Abdominal Aortic Aneurysm in the ApoE Knockout Mouse: Time Course of Control vs. Angiotensin II Mus musculus Mus musculus
163 Abdominal Aortic Aneurysm in the ApoE Knockout Mouse: Time Course of Control vs. Angiotensin II Mus musculus Mus musculus
164 Estradiol effect on the ischemic brain Rattus norvegicus Rattus norvegicus
165 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
166 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
167 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
168 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
169 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
170 Estradiol effect on ERK1/ERK2-deficient MCF-7 breast adenocarcinoma cells: time course Homo sapiens Homo sapiens
171 Estrogen effect on estrogen receptors alpha and beta single knockouts: aorta Mus musculus Mus musculus
172 Tibolone hormone effect on postmenopausal endometrium Homo sapiens Homo sapiens
173 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
174 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
175 17beta-estradiol and genistein effect on thymus: time course Mus musculus Mus musculus
176 Progesterone effect on cultured neonatal ovaries Rattus norvegicus Rattus norvegicus
177 ob/ob liver response to low doses of leptin Mus musculus Mus musculus
178 ob/ob liver response to low doses of leptin Mus musculus Mus musculus
179 Leptin effect on gallbladder Mus musculus Mus musculus
180 Aldosterone response Mus musculus Mus musculus
181 Estrogen effect on bone marrow-derived c-kit+ stem cells and CD44+ stromal cells Mus musculus Mus musculus
182 CD3+ T cell response to stimulation with CD3/CD28 or nitric oxide Homo sapiens Homo sapiens
183 Calcium-signaling effects on blastocyts Mus musculus Mus musculus
184 The organizational effects of testosterone on brain DNA methylome Mus musculus Mus musculus
185 The organizational effects of testosterone on brain DNA methylome Mus musculus Mus musculus
186 The organizational effects of testosterone on brain DNA methylome Mus musculus Mus musculus
187 The organizational effects of testosterone on brain DNA methylome Mus musculus Mus musculus
188 ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal Via the PI3K/AKT Pathway Homo sapiens Homo sapiens
189 Uterine Transcriptional Profile Following Treatment with Estradiol or Synthetic Estrogens Diethylstilbestrol and Propyl Pyrazole Triol Mus musculus Mus musculus
190 Uterine Transcriptional Profile Following Treatment with Estradiol or Synthetic Estrogens Diethylstilbestrol and Propyl Pyrazole Triol Mus musculus Mus musculus
191 Estrogen effect on bone marrow-derived c-kit+ stem cells and CD44+ stromal cells Mus musculus Mus musculus
192 Endothelial cell response to estradiol in vitro Homo sapiens Homo sapiens
193 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
194 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
195 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
196 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
197 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
198 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
199 Uterus response to 17beta-estradiol: time course Mus musculus Mus musculus
200 Cimicifuga racemosa extract effect on breast cancer cell line MCF-7 Homo sapiens Homo sapiens
201 Estradiol effect on breast cancer cell line expressing estrogen receptor: time course Homo sapiens Homo sapiens
202 Estradiol effect on breast cancer cell line expressing estrogen receptor: time course Homo sapiens Homo sapiens
203 Estradiol effect on breast cancer cell line expressing estrogen receptor: time course Homo sapiens Homo sapiens
204 Estradiol effect on breast cancer cell line: time course Homo sapiens Homo sapiens
205 Estradiol effect on breast cancer cell line: time course Homo sapiens Homo sapiens
206 Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen Homo sapiens Homo sapiens
207 Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen Homo sapiens Homo sapiens
208 Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen Homo sapiens Homo sapiens
209 Progesterone and Hoxa-10 relationship Mus musculus Mus musculus
210 Progesterone and Hoxa-10 relationship Mus musculus Mus musculus
211 Estrogen effect on lung: time course Mus musculus Mus musculus
212 Estrogen effect on lung: time course Mus musculus Mus musculus
213 Estrogen effect on lung: time course Mus musculus Mus musculus
214 Estrogen effect on lung: time course Mus musculus Mus musculus
215 Testosterone effect on the female submandibular gland Mus musculus Mus musculus
216 Prostate response to castration and subsequent hormone replacement Mus musculus Mus musculus
217 Progesterone effects on uterus time course Mus musculus Mus musculus
218 Interleukin-20 subfamily cytokines effect on epidermal keratinocytes Homo sapiens Homo sapiens
219 IRAK-4 kinase deficient fibroblast response to IL-1: time course Mus musculus Mus musculus
220 IRAK-4 kinase deficient fibroblast response to IL-1: time course Mus musculus Mus musculus
221 IRAK-4 kinase deficient fibroblast response to IL-1: time course Mus musculus Mus musculus
222 IRAK-4 kinase deficient fibroblast response to IL-1: time course Mus musculus Mus musculus
223 Interleukin 6 effect on liver Mus musculus Mus musculus
224 Testosterone effect on skeletal muscles of HIV-infected males experiencing weight loss Homo sapiens Homo sapiens
225 Ovarian cancer intraperitoneal xenograft model Homo sapiens Homo sapiens
226 Ovarian cancer intraperitoneal xenograft model Homo sapiens Homo sapiens
227 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
228 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
229 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
230 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
231 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
232 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
233 Renal clear cell carcinoma-thyroid hormone receptor mutants: HepG3 cell line Homo sapiens Homo sapiens
234 Airway epithelial cell response to IL-13 in vitro Homo sapiens Homo sapiens
235 Retinoic acid effect on CD4+ T cells from spleen/lymph nodes Mus musculus Mus musculus
236 Filarial nematode asparaginyl-tRNA synthetase effect on immature dendritic cells Homo sapiens Homo sapiens
237 Estrogen response uterine gene profile in Ex3αERKO Mus musculus Mus musculus
238 Estrogen response uterine gene profile in Ex3αERKO Mus musculus Mus musculus
239 Estrogen response uterine gene profile in Ex3αERKO Mus musculus Mus musculus
240 Estrogen response uterine gene profile in Ex3αERKO Mus musculus Mus musculus
241 Unique signatures of estrogen independent growth of MCF-7 cells in low-estrogen versus complete estrogen depravation Homo sapiens Homo sapiens
242 Bone morphogenetic protein 4 effect on a stem cell line Mus musculus Mus musculus
243 Unique signatures of estrogen independent growth of MCF-7 cells in low-estrogen versus complete estrogen depravation Homo sapiens Homo sapiens
244 Unique signatures of estrogen independent growth of MCF-7 cells in low-estrogen versus complete estrogen depravation Homo sapiens Homo sapiens
245 Unique signatures of estrogen independent growth of MCF-7 cells in low-estrogen versus complete estrogen depravation Homo sapiens Homo sapiens
246 The expression patterns of 17b-estradiol responsive genes in wt MCF7, OHT resistant MCF7 and ICI resistant MCF7 Homo sapiens Homo sapiens
247 The expression patterns of 17b-estradiol responsive genes in wt MCF7, OHT resistant MCF7 and ICI resistant MCF7 Homo sapiens Homo sapiens
248 The expression patterns of 17b-estradiol responsive genes in wt MCF7, OHT resistant MCF7 and ICI resistant MCF7 Homo sapiens Homo sapiens
249 Expression data from female reproductive organs of adult mice treated with estrogen Mus musculus Mus musculus
250 Expression data from female reproductive organs of adult mice treated with estrogen Mus musculus Mus musculus
251 Expression data from female reproductive organs of adult mice treated with estrogen Mus musculus Mus musculus
252 Estrogen effect on breast cancer cell line: time course Homo sapiens Homo sapiens
253 Fibroblast growth factor 2 restimulation effect on embryonic fibroblast Homo sapiens Homo sapiens
254 Estrogen effect on breast cancer cell line: time course Homo sapiens Homo sapiens
255 Estrogen effect on breast cancer cell line: time course Homo sapiens Homo sapiens
256 Estradiol Induced Transcriptional Profile of EAAE DNA Binding Deficient ERa Uterus Mus musculus Mus musculus
257 Estradiol Induced Transcriptional Profile of EAAE DNA Binding Deficient ERa Uterus Mus musculus Mus musculus
258 17β-estradiol accelerates ovarian tumour progression in vivo though the upregulation of GREB1 Mus musculus Mus musculus
259 Effect of estradiol on murine alveolar macrophages and RAW264.7 cells in vitro Mus musculus Mus musculus
260 Estrogen effect on male and female haematopoietic stem cells Mus musculus Mus musculus
261 Estrogen effect on male and female haematopoietic stem cells Mus musculus Mus musculus
262 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
263 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
264 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
265 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
266 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
267 Active FOXO1 is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming Homo sapiens Homo sapiens
268 ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal Via the PI3K/AKT Pathway Homo sapiens Homo sapiens
269 ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal Via the PI3K/AKT Pathway Homo sapiens Homo sapiens
270 TLR4 senses oxidative stress mediated by partially oxidized microvesicles. Mus musculus Mus musculus
271 Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants Mus musculus Mus musculus
272 Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants Mus musculus Mus musculus
273 Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants Mus musculus Mus musculus
274 Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants Mus musculus Mus musculus
275 Isoproterenol-induced cardiomyopathy and exercise-induced cardiac hypertrophy Mus musculus Mus musculus

PCA

Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.

Genes

Hierarchical clustering of genes based on weights from the differential expression method.

Enrichr

Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.

Hierarchical clustering of enriched terms from

L1000CDS2

L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.