Name

ATP23 Gene

ATP23 metallopeptidase and ATP synthase assembly factor homolog

The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

ATP23 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the ATP23 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

Peptidase M76, ATP23 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase M76, ATP23 protein domain from the InterPro Predicted Protein Domain Annotations dataset.