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ATP23 GeneATP23 metallopeptidase and ATP synthase assembly factor homolog The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] |
ATP23 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the ATP23 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
Peptidase M76, ATP23 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Peptidase M76, ATP23 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |