What's New in Harmonizome 3.0?

New Datasets

• DeepCoverMOA Mechanisms of Actions
• Protein expression profiles in HCT116 cell line following drug treatment
• DisGeNET Gene-Disease Associations
• Gene-disease associations sourced from curated repositories, GWAS catalogues, animal models and the scientific literature
• DisGeNET Gene-Phenotype Associations
• Gene-phenotype associations sourced from curated repositories, GWAS catalogues, animal models and the scientific literature
• Kinase Library Serine Threonine Kinase Atlas
• A phosphoproteomics atlas detailing phosphorylation of protein substrates by 303 serine/threonine kinases in the human kinome
• KnockTF Gene Expression Profiles with Transcription Factor Perturbations
• Gene expression profiles for cell lines or tissues following transcription factor perturbation (knockdown/knockout)
• Sanger Cancer Dependency Map Cancer Cell Line Proteomics
• Protein intensity values acquired using data-independent acquisition mass spectrometry (DIA-MS)
• Tabula Sapiens Gene-Cell Associations
• Gene expression counts for single human cells

New Download Type

Knowledge Graph Serializations

A compressed folder containing serialized dataset associations ready for knowledge graph ingestion in multiple formats:

• RDF
• JSON
• TSV

New Visualizations