Harmonizome 3.0

ash2 (absent, small, or homeotic)-like (Drosophila) pseudogene 1

ash1 (absent, small, or homeotic)-like (Drosophila)

This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]

absent in melanoma 1-like

Predicted to enable carbohydrate binding activity. [provided by Alliance of Genome Resources, Mar 2025]

ash2 (absent, small, or homeotic)-like (Drosophila) pseudogene

ash2 (absent, small, or homeotic)-like (Drosophila) pseudogene

ash2 (absent, small, or homeotic)-like (Drosophila) pseudogene

ash2 (absent, small, or homeotic)-like (Drosophila) pseudogene

absent in melanoma 1

Predicted to enable carbohydrate binding activity. [provided by Alliance of Genome Resources, Mar 2025]

absent in melanoma 2

AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]

ash2 (absent, small, or homeotic)-like (Drosophila)

Enables beta-catenin binding activity and transcription cis-regulatory region binding activity. Involved in positive regulation of cell population proliferation; response to estrogen; and transcription initiation-coupled chromatin remodeling. Acts upstream of or within DNA damage response. Located in nucleus. Part of MLL1 complex; MLL3/4 complex; and Set1C/COMPASS complex. [provided by Alliance of Genome Resources, Mar 2025]

cataract, congenital, with microphthalmia

Cataract, congenital cerulean type, 5

Cataract, autosomal recessive congenital 3

cataract, congenital nuclear, autosomal recessive

cataract, anterior polar 1

cataract, anterior polar 2

Cataract, posterior polar, 5

Cataract, central pouch-like, with sutural opacities

Cataract, congenital, nuclear progressive

Cataract 28

cataract, pulverulent (autosomal recessive, early-onset)

cataract, congenital, cerulean type, 1

cataract, congenital, total

cataract, congenital, Volkmann type

Cataract 29, coralliform

Deafness, cataract, retinitis pigmentosa, and sperm abnormalities

Cataract, posterior polar