Name

TYR Gene

tyrosinase

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

OARD1 Gene

O-acyl-ADP-ribose deacylase 1

The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop. [provided by RefSeq, Jul 2016]

DTD2 Gene

D-tyrosyl-tRNA deacylase 2 (putative)

Enables Ala-tRNA(Thr) hydrolase activity. Involved in aminoacyl-tRNA metabolism involved in translational fidelity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

DTD1 Gene

D-tyrosyl-tRNA deacylase 1

The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

TRY-GTA10-1 Gene

transfer RNA-Tyr (GTA) 10-1

TRY-GTA1-1 Gene

transfer RNA-Tyr (GTA) 1-1

TRY-ATA1-1 Gene

transfer RNA-Tyr (ATA) 1-1

TRY-GTA5-2 Gene

transfer RNA-Tyr (GTA) 5-2

TRY-GTA5-3 Gene

transfer RNA-Tyr (GTA) 5-3

TRY-GTA5-1 Gene

transfer RNA-Tyr (GTA) 5-1

TRY-GTA5-4 Gene

transfer RNA-Tyr (GTA) 5-4

TRY-GTA5-5 Gene

transfer RNA-Tyr (GTA) 5-5

TRY-GTA2-1 Gene

transfer RNA-Tyr (GTA) 2-1

TRY-GTA12-1 Gene

transfer RNA-Tyr (GTA) 12-1

TRY-GTA6-1 Gene

transfer RNA-Tyr (GTA) 6-1

TRY-GTA7-1 Gene

transfer RNA-Tyr (GTA) 7-1

TRY-GTA11-1 Gene

transfer RNA-Tyr (GTA) 11-1

TRY-GTA3-1 Gene

transfer RNA-Tyr (GTA) 3-1

TRY-GTA4-1 Gene

transfer RNA-Tyr (GTA) 4-1

TRY-GTA8-1 Gene

transfer RNA-Tyr (GTA) 8-1

TRY-GTA9-1 Gene

transfer RNA-Tyr (GTA) 9-1