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Results for "HIN-200/IF120x": 2 genes, 2 gene sets

Name

PYHIN1 Gene

pyrin and HIN domain family, member 1

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

LOC646377 Gene

pyrin and HIN domain family, member 1 pseudogene

HIN-200/IF120x Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HIN-200/IF120x protein domain from the InterPro Predicted Protein Domain Annotations dataset.

hin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.