Results for "Loose Anagen Hair Syndrome": 9 genes

Name

HRM2 Gene

hair, curly

ECTD5 Gene

Ectodermal dysplasia 5, hair/nail type

ECTD7 Gene

Ectodermal dysplasia 7, hair/nail type

ECTD6 Gene

Ectodermal dysplasia 6, hair/nail type

ECTD8 Gene

Ectodermal dysplasia 8, hair/tooth/nail type

SHEP8 Gene

Skin/hair/eye pigmentation 8, freckling

HCL2 Gene

hair color 2 (red)

HCL1 Gene

hair color 1 (brown)

HR Gene

hair growth associated

This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]