Results for "MULE transposase domain": 4 genes

Name

SETMAR Gene

SET domain and mariner transposase fusion gene

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

HARBI1 Gene

harbinger transposase derived 1

Predicted to enable metal ion binding activity and nuclease activity. Located in centriolar satellite; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

L1TD1 Gene

LINE-1 type transposase domain containing 1

Predicted to enable single-stranded RNA binding activity. Predicted to be involved in retrotransposition. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

L1TD1P1 Gene

LINE-1 type transposase domain containing 1 pseudogene 1